起搏诱导性心肌病的临床研究进展OA
Advances in clinical research of pacing-induced cardiomyopathy
起搏诱导性心肌病(pacing-induced cardiomyopathy,PICM)是长期右心室起搏导致左心室收缩功能进行性下降的一种严重并发症.随着永久性心脏起搏器植入数量的逐年上升,PICM的早期识别与有效防治已成为心血管领域关注的重点.本文系统回顾PICM的定义、流行病学特点、病理生理机制、危险因素及相关预测模型,并依据现有循证证据,对心脏再同步化治疗、传导系统起搏以及生物起搏等防治策略的效果与局限进行评述,以期为临床管理提供参考.
Pacemaker-induced cardiomyopathy(PICM)is a serious complication characterized by progressive deterioration of left ventricular systolic function due to chronic right ventricular pacing.With the annual increase in permanent pacemaker implantations,the early identification and effective management of PICM have become key concerns in the field of cardiology.This article systematically reviews the definition,epidemiological features,pathophysiological mechanisms,risk factors,and related predictive models of PICM.Based on current evidences,it evaluates the effect and limitations of preventive and therapeutic strategies including cardiac resynchronization therapy,conduction system pacing,and biological pacing,aiming to provide insights for clinical practice.
张磊;徐素丹;李红莉
200080 上海,上海交通大学医学院附属上海市第一人民医院老年科200080 上海,上海交通大学医学院附属上海市第一人民医院老年科200080 上海,上海交通大学医学院附属上海市第一人民医院老年科
医药卫生
起搏诱导性心肌病右心室起搏永久性心脏起搏器心脏再同步化治疗传导系统起搏
pacing-induced cardiomyopathyright ventricular pacingpermanent pacemakercardiac resynchronization therapyconduction system pacing
《实用心电与临床诊疗》 2026 (1)
144-151,8
上海交通大学医工交叉重点项目(YG2021ZD19)
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