磨牙-切牙釉质矿化不全诊疗策略研究进展OA
Advancements in the diagnosis and treatment strategies for molar-incisor hypomineralization
磨牙-切牙釉质矿化不全(molar-incisor hypomineralization,MIH)是一种牙釉质发育缺陷性疾病,主要表现为第一恒磨牙和恒切牙的釉质矿化异常.由于矿化不充分,MIH患牙易发生牙体缺损和龋坏,进而继发牙齿敏感、咬合问题等.MIH诊断主要依据围产期及婴幼儿时期的相关病史、病损的牙位特征及病损轮廓.根据釉质缺损的范围及严重程度,MIH可分为轻型和重型.诊疗策略强调早期筛查、诊断和干预;预防为主,对症治疗,以及定期复查.轻型MIH主要表现为牙釉质的脱矿性白斑或色泽改变,通常不伴随釉质剥脱;治疗以预防龋坏和美学修复为主,常用方法包括再矿化、微研磨、树脂浸润治疗、漂白治疗、局部涂氟、窝沟封闭等.重型MIH通常表现为严重的脱矿性釉质白斑且伴有釉质剥脱,还可能伴随龋坏、牙齿敏感等;治疗主要为修复牙体缺损或对于无法保留的患牙拔除后正畸治疗等,但常需综合多种治疗方法以恢复牙齿及牙列的功能和美观.本文对MIH的诊疗策略研究进展进行综述,为临床诊疗提供参考.
Molar-incisor hypomineralization(MIH)is a developmental defect of enamel that is characterized primar-ily by abnormal enamel mineralization affecting the first permanent molars and permanent incisors.Due to insufficient mineralization,teeth affected by MIH are prone to post-eruptive breakdown and caries,potentially leading to sequelae such as tooth sensitivity and occlusal problems.The diagnosis of MIH is primarily based on relevant perinatal and infan-tile medical history,the characteristic distribution of affected teeth,and the morphological features of the enamel de-fects.Based on the extent and severity of the enamel defect,MIH is classified as mild or severe.Diagnosis and treat-ment strategies emphasize early screening,diagnosis,and intervention,prioritizing prevention,providing symptomatic care,and implementing regular recall assessments.Mild MIH predominantly manifests as demineralized enamel opaci-ties or discoloration,typically without significant enamel breakdown.Treatment focuses on caries prevention and aes-thetic restoration,employing techniques such as remineralization,micro-abrasion,resin infiltration,bleaching,fluoride application,and fissure sealants.Severe MIH typically presents with extensive enamel opacities accompanied by sub-stantial enamel breakdown and may be complicated by caries and tooth sensitivity.Management primarily involves re-storing the structural defects or,for teeth that cannot be preserved,extraction followed by orthodontic treatment.Com-prehensive management often requires a multimodal approach integrating various therapeutic modalities to restore both the function and aesthetics of the affected teeth and overall dentition.This article provides a review of advancements in diagnosis and the treatment strategies for MIH,offering a reference for clinical practice.
赵芳;王欣;黄进伟;刘景平;徐赫
北京大学口腔医学院·口腔医院儿童口腔科,北京(100081)||呼和浩特市口腔医院(内蒙古自治区口腔医院)儿童牙病科,内蒙古自治区 呼和浩特(010030)北京大学口腔医学院·口腔医院儿童口腔科,北京(100081)北京大学口腔医学院·口腔医院综合治疗二科,北京(100081)呼和浩特市口腔医院(内蒙古自治区口腔医院)儿童牙病科,内蒙古自治区 呼和浩特(010030)北京大学口腔医学院·口腔医院儿童口腔科,北京(100081)
医药卫生
磨牙-切牙釉质矿化不全牙釉质发育缺陷第一恒磨牙切牙诊疗策略龋病牙体缺损口腔健康
molar-incisor hypomineralizationdevelopmental defects of enamelfirst permanent molarinci-sordiagnosis and treatment strategiesdental cariesdental defectsoral health
《口腔疾病防治》 2026 (3)
292-301,10
北京市自然科学基金面上项目(7242172)北京大学口腔医院临床新技术新疗法项目(PKUSSNCT-25A13) This study was supported by the grants from Beijing Natural Science Foundation General Program(No.7242172)Pro-gram for New Clinical Techniques and Therapies of Peking University School and Hospital of Stomatology(No.PKUSSNCT-25A13).
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