TEAS和穴位按压对乳腺癌围化疗期患者生活质量的影响:随机对照试验OA
Effects of TEAS and acupoint pressing on the quality of life of breast cancer patients during perioperative chemotherapy:a randomized controlled trial
目的:观察经皮穴位电刺激(TEAS)和穴位按压对乳腺癌围化疗期患者生活质量、睡眠质量及焦虑抑郁的影响.方法:将150例乳腺癌围化疗期患者随机分为TEAS组、穴位按压组和常规治疗组,每组50例.常规治疗组接受化疗方案及对症治疗,TEAS组与穴位按压组在此基础上分别予TEAS与穴位按压,穴位均选择双侧合谷、内关、足三里、三阴交.治疗均持续4个化疗周期.在基线期(T0)和每个化疗周期结束后第1天(T1、T2、T3、T4),比较各组患者乳腺癌患者生命质量测定量表(FACT-B)、匹兹堡睡眠质量指数(PSQI)及医院焦虑和抑郁量表(HADS)评分,并进行安全性评价.结果:与T0比较,TEAS组患者T4 FACT-B评分升高(P＜0.05).TEAS组化疗后各时间点FACT-B评分高于常规治疗组(P＜0.05),T2、T3、T4 FACT-B评分高于穴位按压组(P＜0.05);穴位按压组T2、T4 FACT-B评分高于常规治疗组(P＜0.05).TEAS组患者T2、T3、T4 PSQI评分低于常规治疗组(P＜0.05),T4 PSQI评分低于穴位按压组(P＜0.05);穴位按压组T2 PSQI评分低于常规治疗组(P＜0.05).与T0比较,穴位按压组患者化疗后各时间点HADS评分均降低(P＜0.05).穴位按压组患者T1、T4 HADS评分低于常规治疗组(P＜0.05).结论:TEAS 与穴位按压均可提高乳腺癌围化疗期患者生活质量,TEAS 在改善睡眠质量方面更优,穴位按压在改善焦虑抑郁方面更佳.
Objective To observe the effects of transcutaneous electrical acupoint stimulation(TEAS)and acupoint pressing on the quality of life,sleep quality,and anxiety and depression in breast cancer patients during perioperative chemotherapy.Methods A total of 150 breast cancer patients during perioperative chemotherapy were randomly assigned to a TEAS group,an acupoint pressing group,and a conventional treatment group,50 cases in each group.Patients in the conventional treatment group received routine chemotherapy and symptomatic treatment,while patients in the TEAS group and the acupoint pressing group received TEAS and acupressure respectively on this basis.The selected acupoints included both sides of Hegu(LI4),Neiguan(PC6),Zusanli(ST36),and Sanyinjiao(SP6),applied throughout four chemotherapy cycles.At baseline(T0)and the first day after the end of each chemotherapy cycle(T1,T2,T3,T4),functional assessment of cancer therapy-breast(FACT-B),Pittsburgh sleep quality index(PSQI)and hospital anxiety and depression scale(HADS)scores of patients in each group were compared,and the safety was evaluated.Results Compared with T0,the FACT-B score of the TEAS group at T4 was increased(P＜0.05).The FACT-B scores at each time point after chemotherapy in the TEAS group were higher than those in the conventional treatment group(P＜0.05),and the FACT-B scores at T2,T3 and T4 were higher than those in the acupoint pressing group(P＜0.05).The FACT-B scores of the acupoint pressing group at T2 and T4 were higher than those of the conventional treatment group(P＜0.05).The PSQI scores of the TEAS group at T2,T3 and T4 were lower than those of the conventional treatment group(P＜0.05),and the PSQI score at T4 was lower than that in the acupoint pressing group(P＜0.05).The PSQI score of the acupoint pressing group at T2 was lower than that of the conventional treatment group(P＜0.05).Compared with T0,the HADS scores of the acupoint pressing group were decreased at each time point after chemotherapy(P＜0.05).The HADS scores of the acupoint pressing group at T1 and T4 were lower than those of the conventional treatment group(P＜0.05).Conclusion Both TEAS and acupoint pressing can improve the quality of life of breast cancer patients during perioperative chemotherapy.TEAS is more effective in improving sleep quality,while acupoint pressing is better at alleviating anxiety and depression.
韩金书;杨义;李苑;田超;朱冰梅;褚婕;袁将;栗浩;吐玛丽斯·卡依沙尔;陶芝榛
成都中医药大学,临床医学院,四川 成都 611137成都中医药大学,管理学院,四川 成都 611137成都中医药大学,公共卫生学院,四川 成都 611137四川省肿瘤医院乳腺科四川大学华西医院,再生医学研究中心电子科技大学医学院成都中医药大学,公共卫生学院,四川 成都 611137四川大学华西医院,再生医学研究中心||四川大学华西医院,中西医结合内科成都中医药大学,公共卫生学院,四川 成都 611137成都中医药大学,公共卫生学院,四川 成都 611137
乳腺癌围化疗期经皮穴位电刺激穴位按压生活质量
breast cancerperioperative chemotherapytranscutaneous electrical acupoint stimulationacupoint pressingquality of life
《中国针灸》 2026 (2)
206-210,5
成都中医药大学"杏林学者"学科人才项目:QJRC2021021护理学四川省重点实验室 2023 年度开放课题项目:HLKF2023(Z)-1成都中医药大学大学生创新创业训练计划项目:202410633074
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