脑梗死患者心脏瓣膜术后近期死亡的危险因素分析OA
Risk Factors for Short-term Mortality After Heart Valve Surgery in Patients Complicated With Preoperative Cerebral Infarction
目的 探讨脑梗死患者心脏瓣膜术后30 d死亡的危险因素.方法 回顾性收集2010年1月1日至2022年7月31日本中心435例接受心脏瓣膜手术脑梗死患者的临床资料,利用单因素和多因素Logistic回归分析探究术后30 d死亡的危险因素.结果 全组患者术后30 d死亡率为8.51%.多因素Logistic回归分析发现:术前慢性肺部疾病史(OR=9.184,95%CI:2.132～39.560,P=0.003)、身体质量指数(BMI)增加(OR=1.147,95%CI:1.017～1.294,P=0.026)和内生肌酐清除率降低(OR=0.977,95%CI:0.955～0.999,P=0.037)是术后30 d内死亡的独立危险因素.结论 术前合并慢性肺部疾病、BMI增加和内生肌酐清除率降低是脑梗死患者心脏瓣膜术后30 d死亡的独立危险因素.
Objective To explore the risk factors for 30-day mortality after heart valve surgery in patients complicated with preoperative cerebral infarction.Methods From January 1st,2010 to July 31st,2022,435 consecutive patients complicated with preoperative cerebral infarction,who underwent heart valve surgery in our center,were enrolled retrospectively.Univariable and multivariable logistic analyses were performed to identify predictors of 30-day mortality.Results 30-day mortality was 8.51%overall among the 435 patients.Multivariable logistic analysis showed that preoperative chronic lung disease(OR=9.184,95%CI:2.132-39.560,P=0.003),higher BMI(OR=1.147,95%CI:1.017-1.294,P=0.026)and lower endogenous creatinine clearance rate(OR=0.977,95%CI:0.955-0.999,P=0.037)were independent risk factors.Conclusion Preoperative chronic lung disease,higher BMI and lower endogenous creatinine clearance rate were independent risk factors for 30-day mortality in patients complicated with preoperative cerebral infarction,who underwent heart valve surgery.
高竣迪;孙广龙;伯平;谢进生
首都医科大学附属北京安贞医院体外循环及机械循环辅助科,北京 100029首都医科大学附属北京安贞医院微创心脏外科中心,北京 100029首都医科大学附属北京安贞医院微创心脏外科中心,北京 100029首都医科大学附属北京安贞医院微创心脏外科中心,北京 100029
脑梗死心脏瓣膜手术危险因素
cerebral infarctionheart valve surgeryrisk factor
《中国体外生命支持》 2026 (1)
13-17,24,6
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