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关注终末期肝病合并感染的临床诊治OA

Focusing on clinical diagnosis and treatment of end-stage liver disease complicated with infection

中文摘要英文摘要

终末期肝病患者因免疫功能低下、肠道菌群紊乱、有创操作增多等原因,感染风险显著升高,且感染后病情进展快、死亡率高.终末期肝病合并感染的诊治需结合患者基础肝病状态、感染部位及病原体特点,早期识别、精准抗感染和综合支持治疗.文章主要对终末期肝病合并感染的流行病学与高危因素、临床特点、诊断和治疗等方面进行阐述,旨在进一步提高临床医生对终末期肝病合并感染的认识及救治能力.

The patients with end-stage liver disease have a significantly increased risk of infection due to reasons of weakened immune function,disordered intestinal flora,and increased invasive procedures.The end-stage liver disease complicated with infection progresses rapidly and the mortality rate is high.The diagnosis and treatment of end-stage liver disease complicated with infection should be based on the patient's underlying liver disease status,the site of infection and the characteristics of the pathogen.It requires early identification,precise anti-infection and comprehensive supportive treatment.This article mainly reviews the epidemiology and high-risk factors,clinical characteristics,diagnosis and treatment of end-stage liver disease complicated with infection,aiming to further improve clinicians' understanding of end-stage liver disease complicated with infection,and improve their treatment capabilities.

丁洋;窦晓光

中国医科大学附属盛京医院感染科辽宁省病毒性肝炎重点实验室,辽宁沈阳 110022中国医科大学附属盛京医院感染科辽宁省病毒性肝炎重点实验室,辽宁沈阳 110022

医药卫生

终末期肝病感染诊断治疗

end-stage liver diseaseinfectiondiagnosistreatment

《中国实用内科杂志》 2026 (2)

89-91,3

辽宁省科技厅应用基础研究计划项目(2022JH2/101500009)

10.19538/j.nk2026020101

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