人参活性成分免疫调节作用机制及其在疾病治疗中应用的研究进展OA
Research Progress on the Immunomodulatory Mechanism of Ginseng Active Ingredients and Its Application in the Treatment of Diseases
人参属于补气药物,性味甘微苦平,具有大补元气、生津和安神的功效.人参主要活性成分包括人参皂苷、人参多糖、挥发油和氨基酸等,这些成分可通过免疫调节发挥抗糖脂代谢紊乱、抗动脉粥样硬化、抗肿瘤、抗炎和抗氧化等药理作用,因此,人参活性成分在代谢性疾病、肿瘤、骨关节疾病以及呼吸系统疾病等领域具有潜在应用价值.本文对人参活性成分通过免疫调节治疗各类疾病的药理作用进行综述并阐明其作用机制,为中药新药和保健产品的研发提供潜在的参考,也为人参活性成分通过免疫治疗各类疾病的基础研究与临床应用提供理论依据.
Ginseng is a qi-tonifying herb with the properties of sweet,slightly bitter,and neutral taste.It is known for its effects of replenishing vital energy,promoting the production of body fluids,and calming the mind.The main active components of ginseng include ginsenosides,ginseng polysaccharides,volatile oils,and amino acids.These components have significant immunomodulatory effects on the human body and can exert actions against metabolic disorders,atherosclerosis,tumors,inflammation,and oxidation through immune regulation.Therefore,the active components of ginseng have potential applications in the fields of metabolic diseases,tumors,bone and joint diseases,and respiratory diseases.This article reviews the pharmacological effects of ginseng active components in treating various diseases through immune regulation and elucidates the mechanisms of action.It provides potential resources for the development of new traditional Chinese medicine drugs and health products,and also offers theoretical basis for the basic research and clinical application of ginseng active components in immunotherapy of various diseases.
李静;孙志远;周铄;徐林一;罗浩铭;房晓雪
长春中医药大学药学院,长春 130117长春中医药大学中医学院,长春 130117长春中医药大学药学院,长春 130117长春中医药大学药学院,长春 130117长春中医药大学药学院,长春 130117长春中医药大学药学院,长春 130117
化学化工
人参活性成分免疫系统作用机制糖尿病动脉粥样硬化肿瘤骨关节疾病呼吸系统疾病
Ginseng active ingredientImmune systemMechanism of actionDiabetes mellitusAtherosclerosisTumorsBone and joint diseasesRespiratory diseases
《应用化学》 2026 (2)
182-194,13
国家自然科学基金(No.82304913)和吉林省科学技术厅项目(No.YDZJ202501ZYTS803)资助 Supported by the National Natural Science Foundation of China(No.82304913)and the Department of Science and Technology of Jilin Province(No.YDZJ202501ZYTS803)
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