首页|期刊导航|生命科学仪器|中性粒细胞和淋巴细胞比值与急性心肌梗死PCI术后预后的相关性

中性粒细胞和淋巴细胞比值与急性心肌梗死PCI术后预后的相关性OA

Correlation between Neutrophils And Lymphocytes Ratio And Prognosis after PCI for Acute Myocardial Infarction

中文摘要英文摘要

目的 分析对急性心肌梗死(AMI)患者采取经皮冠状动脉介入治疗(PCI)后中性粒细胞和淋巴细胞比值(NLR)与其预后的相关性.方法 回顾性分析医院2021年1月至2023年5月收治的采取PCI术治疗的228例AMI患者的临床资料,术后采集5 ml空腹外周肘静脉血,检测中性粒细胞(NE)、淋巴细胞(LYM),并计算NLR,根据术后NLR高低将其分为甲组(NLR排序为1~114号的患者)和乙组(NLR排序为115~228号的患者).观察对比两组NE、LYM平均值以及NLR平均值,统计术后6个月两组心血管不良事件发生情况,分析NLR与患者预后的相关性.结果 甲组NE平均值高于乙组(P<0.05),LYM平均值低于乙组(P<0.05),NLR平均值高于乙组(P<0.05).PCI术后6个月,甲组心血管不良事件总发生率高于乙组(P<0.05).PCI术后AMI患者的预后与其NLR存在一定的关联,尤其是心源性死亡、心力衰竭、心律失常的发生,与NLR存在明显的相关性(r>0,P<0.05).结论 对于AMI患者,在采取PCI术治疗后,需密切关注其NLR变化情况,其NLR上升,可能预示心源性死亡、心力衰竭、心律失常等不良预后.

Objective:To analyze the correlation between the ratio of neutrophil to lymphocyte(NLR)and prognosis in patients with acute myocardial infarction(AMI)after percutaneous coronary intervention(PCI).Methods:The clinical data of 228 AMI patients treated by PCI in our hospital from January 2021 to May 2023 were retrospectively analyzed.After operation,5 ml of fasting peripheral elbow venous blood was collected,neutrophils(NE)and lym-phocytes(LYM)were detected,and NLR was calculated.According to the postoperative NLR,the patients were divided into group A(patients with NLR ranking from 1 to 114)and group B(patients with NLR ranking from 115).The mean values of NE、LYM and NLR in the two groups were observed and compared,and the incidence of cardiovascular adverse events in the two groups was counted 6 months after operation,and the correlation between NLR and the prognosis of patients was analyzed.Results:The average value of NE in group A was higher than that in group B(P<0.05),the average value of LYM was lower than that in group B(P<0.05),and the average value of NLR was higher than that in group B(P<0.05).Six months after PCI,the total incidence of cardiovascular ad-verse events in group A was higher than that in group B(P<0.05).The prognosis of AMI patients after PCI is re-lated to NLR,especially the occurrence of cardiac death,heart failure and arrhythmia,which is obviously related to NLR(r>0,P<0.05).Conclusion:After PCI,patients with AMI should pay close attention to the changes of NLR.The increase of NLR may predict the adverse prognosis such as cardiac death,heart failure and arrhythmia.

谢舒;邵华;陈明星

扬州大学,江苏 扬州 225000||江苏省扬州友好医院心内科,江苏 扬州 225000扬州大学,江苏 扬州 225000||江苏省扬州友好医院心内科,江苏 扬州 225000扬州大学,江苏 扬州 225000||江苏省苏北人民医院心内科,江苏 扬州 225001

医药卫生

中性粒细胞淋巴细胞比值急性心肌梗死PCI术预后

NeutrophilsLymphocyteRatioAcute myocardial infarctionPCIPrognosis

《生命科学仪器》 2026 (1)

22-24,3

10.11967/2026240208

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