布比卡因脂质体用于臂丛神经阻滞联合全麻对肩关节镜手术患者的术后镇痛效果及安全性OA

Objective:To investigate the postoperative analgesic effect and safety of bupivacaine liposome in brachial plexus block combined with general anesthesia for patients undergoing shoulder arthroscopy.Methods:From Janu-ary 2024 to June 2025,62 patients who underwent arthroscopic shoulder surgery in Danyang Maternal and Child Health Hospital were randomly divided into two groups.The control group(31 cases)was given 0.375%ropiva-caine combined with general anesthesia,and the observation group(31 cases)was given bupivacaine liposome com-bined with general anesthesia.The times of pressing analgesia pump and remedial analgesia were compared be-tween the two groups,and the degree of pain at each time point after operation was evaluated,and the adverse re-actions of the two groups were counted.Results:The times of pressing analgesia pump and remedial analgesia in the observation group were less than those in the control group(P<0.05).The NRS scores of the observation group at 6 h、12 h、24 h、48 h and 72 h after operation were lower than those of the control group(P<0.05).The adverse re-action rate of the observation group was lower than that of the control group(P<0.05).Conclusion:Bupivacaine li-posome brachial plexus block combined with general anesthesia can improve postoperative analgesia effect,reduce the use of postoperative remedial analgesia measures and reduce adverse reactions.