临床Ⅰ期双肺上叶肺腺癌N1-N2期淋巴结转移的高危因素分析OA

Objective:To explore the high risk factors of lymph node metastasis in patients with clinical stage Ⅰ bilateral up-per lobe lung adenocarcinoma.Methods:From January 2020 to December 2023,the clinical data of 347 patients with stage I bilateral upper lobe lung adenocarcinoma who underwent standard lobectomy combined with hilar mediastinal lymph node biopsy/dissection in the First Affiliated Hospital of China University of Science and Technology were retrospectively ana-lyzed,and the high risk factors of lymph node metastasis were analyzed.The analysis methods were univariate and multi-variate Logistic regression.Results:Among 347 patients,52(15%)had N1-N2 lymph node metastasis.The risk factors of lymph node metastasis were obtained by univariate analysis,including tumor diameter、pleural invasion、imaging burr sign and differentiation grade.The independent risk factors of lymph node metastasis were obtained by multivariate Logis-tic regression analysis,including tumor diameter and pleural invasion(P<0.05).Conclusion:Tumor diameter and pleural invasion have important predictive value for N1-N2 lymph node metastasis in patients with clinical stage Ⅰ bilateral upper lobe lung adenocarcinoma.