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兰科药用植物二氢菲化合物研究进展OA

Research progress on dihydrophenanthrene compounds from Orchidaceae medicinal plants

中文摘要英文摘要

我国兰科植物资源丰富,来源广泛,很多具有重要的药用价值.研究表明,兰科植物中含有大量二氢菲类化合物,且具有明显的药理活性,可为研发新药提供新颖的结构分子.通过查阅CNKI、PubMed、Scifinder等数据库,系统检索文献,对兰科植物中含二氢菲类化合物的植物、结构类型和特点、药理作用、存在部位等信息进行了总结.其独特的化学结构和广泛药理作用如抗白血病、抗肺癌、抗胃癌、抗炎、抗菌、抗氧化、降糖和降脂等,具有重要的研究价值.

China's Orchidaceae plants are rich in resources and have a wide range of sources,many of which have important medicinal value.Studies have shown that orchids contain a large number of dihydrophenanthrene compounds and have significant pharmacological activities,which can provide novel structural molecules for the development of new drugs.By consulting CNKI,PubMed,Scifinder,and other databases,the literature was systematically searched,and the information of the plants,structure types and characteristics,pharmacological effects,and existence sites of dihydrophenanthrene compounds in orchids were summa-rized.Its unique chemical structure and wide range of pharmacological effects,such as anti-leukemia,anti-lung cancer,anti-gastric cancer,anti-inflammatory,antibacterial,antioxidant,hypoglycemic and lipid-lowering,etc.,have important research value.

卢敏;姬敏;刘辰鹏;谢智任;张小坡;张彩云

海南医科大学药学院,海南 海口 571199海南医科大学药学院,海南 海口 571199海南医科大学药学院,海南 海口 571199海南医科大学药学院,海南 海口 571199海南医科大学药学院,海南 海口 571199海南药物研究与开发科技园,海南 海口 570100

医药卫生

兰科二氢菲药理作用

OrchidaceaeDihydrophenanthrenePharmacological action

《海南医科大学学报》 2026 (3)

223-240,18

This study was supported by the Key Research and Development Project in Hainan Province(ZDYF2022SHFZ037)Hainan Medical University Graduate Innovation Research Project(HYYB2022A17)Hainan Medical University College Student Innovation and Entrepreneurship Training Project(X202311810011)Hainan Medical University Academic Improvement Support Program(XSTS2025132) 海南省重点研发项目(ZDYF2022SHFZ037)海南医科大学研究生创新科研课题(HYYB2022A17)海南医科大学大学生创新创业训练计划(X202311810011)海南医科大学学术提升支撑计划(XSTS2025132)

10.13210/j.cnki.jhmu.20250630.005

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