首页|期刊导航|Traditional Medicine Research|Progress of Ganoderma lucidum in regulating aging-mediated disorders of glycolipid metabolism

Progress of Ganoderma lucidum in regulating aging-mediated disorders of glycolipid metabolismOA

中文摘要

As the aging population continues to grow,age-related health issues are becoming increasingly prominent,attracting widespread attention and concern from society.While research on the mechanisms of aging is relatively extensive,studies on the association between aging and related diseases remain limited.G.lucidum,a traditional medicinal fungus,has garnered significant attention due to its diverse bioactive properties.Recent studies have revealed that G.lucidum and its active components exhibit significant potential in anti-aging and regulating dysregulation of glucose and lipid metabolism.However,a comprehensive and detailed review of recent research findings has yet to be thoroughly explored.This paper summarizes and elucidates the latest advances in the pathological mechanisms of aging-related glucose and lipid metabolism disorders by retrieving data from databases such as X-mol and PubMed,provides a detailed account of the regulatory effects of G.lucidum’s primary active components on aging and lipid metabolism,and explores their potential mechanisms.Additionally,it discusses the application prospects of G.lucidum in the fields of anti-aging and metabolic regulation,aiming to provide a reference for research on aging-mediated lipid metabolism disorders and to lay a theoretical foundation for the further development and application of G.lucidum.

Xiao-Hui Zhao;Xiao-Wei Dai;Hong-Yan Pei;Rui Du;Wei Wang;Zhong-Mei He

College of Chinese Medicinal Materials,Jilin Agricultural University,Changchun 130118,ChinaReproductive Medical Center,Department of Obstetrics and Gynecology,The Second Norman Bethune Hospital of Jilin University,Changchun 130000,ChinaCollege of Chinese Medicinal Materials,Jilin Agricultural University,Changchun 130118,ChinaCollege of Chinese Medicinal Materials,Jilin Agricultural University,Changchun 130118,China School of Pharmacy,Yanbian University,Yanji 133002,ChinaCollege of Humanities and College of Home Economics,Jilin Agricultural University,Changchun 130118,ChinaCollege of Chinese Medicinal Materials,Jilin Agricultural University,Changchun 130118,China

医药卫生

aginglipid metabolismG.lucidum

《Traditional Medicine Research》 2026 (5)

P.68-80,13

supported by grants from Natural Science Foundation of Jilin Province(No.23JQ08,No.YDZJ202502 CXJD077,No.JLARS-2025-0802-09 and No.YDZJ202501ZY TS706).

10.53388/TMR20250710001

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