小儿推拿联合鼻炎膏治疗儿童变应性鼻炎的临床观察OA
Clinical observation of infantile Tuina combined with Bi Yan Gao in treating allergic rhinitis in children
目的:观察刘氏小儿推拿联合鼻炎膏治疗儿童变应性鼻炎(AR)的疗效及对血清炎症因子的影响.方法:共纳入120例AR儿童,按随机数字表法分为推拿组、鼻炎膏组和联合组,每组40例.三组均口服地氯雷他定糖浆作为基础治疗.推拿组采用刘氏小儿推拿治疗,每日1次.鼻炎膏组采用鼻炎膏外涂法,每日早晚各1次.联合组应用刘氏小儿推拿联合鼻炎膏外涂法.共治疗8周.比较治疗前后各组鼻部症状评分(TNSS),检测治疗前后患儿血清白细胞介素(IL)-4、IL-6、IL-8、免疫球蛋白E(IgE)表达水平,并比较各组临床总有效率.结果:治疗8周后,联合组总有效率为87.2%,推拿组为60.5%,鼻炎膏组为57.5%,组间差异有统计学意义(P<0.05).联合组TNSS,血清IL-6、IL-8及IgE含量均低于推拿组和鼻炎膏组,组间差异有统计学意义(P<0.05).三组IL-4水平无统计学差异(P>0.05).结论:刘氏小儿推拿联合鼻炎膏外涂治疗儿童AR可以有效改善患儿的鼻部症状,降低血清炎症因子及IgE水平,临床总有效率高于两种疗法单独使用.
Objective:To observe the efficacy of LIU's infantile Tuina(Chinese therapeutic massage)combined with Bi Yan Gao in treating allergic rhinitis(AR)in kids and the impact on serum inflammatory factors. Methods:A total of 120 kids with AR were recruited and divided into a Tuina group,a Bi Yan Gao group,and a combined group using the random number table method,with 40 cases in each group.The three groups all received oral desloratadine syrup as the basic intervention.In addition,the Tuina group was treated with LIU's infantile Tuina therapy once daily;the BI Yan Gao group received external application of Bi Yan Gao,once every morning and night;the combined group was intervened by LIU's infantile Tuina plus Bi Yan Gao external application.The intervention lasted for 8 weeks.Before and after the intervention,the total nasal symptom score(TNSS)was compared,and the serum levels of interleukin(IL)-4,IL-6,IL-8,and immunoglobulin E(IgE)were detected.The total effective rate was also compared among the three groups. Results:After 8 weeks of treatment,the total effective rate was 87.2%in the combined group,60.5%in the Tuina group,and 57.5%in the Bi Yan Gao group,showing significant between-group differences(P<0.05).The contents of serum IL-6,IL-8,and IgE were lower in the combined group compared to the Tuina and Bi Yan Gao groups,presenting statistical significance(P<0.05).The level of IL-4 was statistically parallel across the three groups(P>0.05). Conclusion:The combined use of LIU's infantile Tuina and Bi Yan Gao can improve nasal symptoms and lower the levels of serum inflammatory factors and IgE in kids with AR,producing a higher total effective rate compared to the separate use of the two approaches.
李秀兰;刘娜;潘琦琦;庞丽婵;何凤诗;黄秋谷;洪珏
医药卫生
推拿按摩小儿推拿鼻炎,变应性白细胞介素免疫球蛋白E儿童随机对照试验
TuinaMassagePediatric TuinaRhinitis,AllergicInterleukinsImmunoglobulin EChildRandomized Controlled Trial
《针灸推拿医学(英文版)》 2026 (1)
87-93,7
This study was supported by the Foshan City's Self-funded Science and Technology Innovation Project in 2022(2022年佛山市自筹经费类科技创新项目,No.2220001005034).
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