中西医结合治疗幽门螺杆菌感染现状及策略OA

This paper systematically reviews the current status of integrated traditional Chinese and western medi-cine in the treatment of Helicobacter pylori(Hp)infection,as well as recent progress in clinical and basic research both in China and internationally.It summarizes the advantages of traditional Chinese medicine(TCM)in Hp infec-tion management,including improving Hp eradication rates,enhancing antibiotic sensitivity,reducing antimicrobial resistance,decreasing drug-related adverse effects,and ameliorating gastric mucosal lesions.These advantages are particularly evident in patients who are intolerant to bismuth-containing regimens,those with refractory Hp infection,and individuals with precancerous gastric lesions.An integrated,whole-process management approach and individual-ized,staged comprehensive treatment strategies combining TCM and western medicine are proposed for Hp infection.Future prevention and control of Hp infection should adopt an integrative Chinese-western medical strategy,emphasiz-ing prevention,strengthening primary care,implementing proactive long-term monitoring,optimizing screening strategies,and advancing the development of novel technologies and mechanistic studies of Chinese herbal inter-ventions.These efforts aim to provide a theoretical basis and practical pathways for the establishment and improve-ment of Hp infection prevention and control systems.