易筋经联合富血小板血浆治疗膝骨关节炎OA

Objective:To undertake a rigorous clinical study to assess the therapeutic efficacy of combining Yi Jin Jing exer-cises with platelet-rich plasma(PRP)in the management of patients with knee osteoarthritis(KOA).Methods:Sixty patients diagnosed with KOA were randomly allocated into two groups of 30 each(control group and observation group).The observation group underwent Yi Jin Jing exercises combined with PRP therapy,whereas the control group participa-ted in isometric quadriceps muscle strengthening exercises paired with PRP therapy,and 30 cases in the observation group were treated with Yi Jin Jing combined with PRP,and the two groups were treated consecutively for 3 months.3 months was 1 course of treatment,and a total of 1 course of treatment was given.The clinical efficacy and recurrence rate of the two groups were compared,as well as the VAS scores,WOMAC scores,levels of inflammatory factors(IL-1β,MMP-3,and TNF-α),and musculoskeletal ultrasound results of the knee joint before and after treatment.Results:Compared to the control group's 46.67%effectiveness(14/30),the observation group achieved 96.67%efficacy(29/30).A significant im-provement was observed in 76.67%of observation group(23/30)versus only 26.67%(8/30)in control group,with the observation group also demonstrating significantly reduced recurrence(P<0.05).VAS scores,WOMAC scores,levels of inflammatory factors IL-1β,MMP-3,TNF-α,synovial thickness and effusion depth decreased in the observation group(P<0.05),and the observation group was significantly better than the control group(P<0.05).No adverse events occurred in both groups.Conclusion:It shows that Yi Jin Jing combined with PRP treatment for KOA can reduce the joint pain and stiffness,improve joint function,reduce the inflam-matory response,lower the recurrence rate,and achieve remarkable clinical efficacy with high safety,making it suit-able for clinical promotion.