痛风性关节炎/痛风石外科诊疗专家共识OA
Expert Consensus on Surgical Management of Gouty Arthritis/Tophi
痛风是一种由嘌呤代谢紊乱和(或)尿酸排泄减少导致高尿酸血症,进而引起单钠尿酸盐(MSU)晶体沉积致机体损伤的代谢性风湿病,可累及关节形成痛风性关节炎,严重影响患者生存质量.尽管降尿酸药物治疗体系在痛风性关节炎/痛风石管理中已发挥了重要作用,但对软组织和(或)关节中的痛风石所导致的结构严重破坏、功能受限或保守治疗无效的顽固性疼痛,通常需要外科干预.为系统提升痛风性关节炎/痛风石外科诊疗的规范化水平,由北京整合医学学会发起,上海市光华中西医结合医院与深圳大学附属华南医院牵头,联合上海中医药研究院关节病研究所,组织国内多家三级甲等医院风湿免疫科、关节外科及骨伤科专家,基于牛津大学循证医学中心(OCEBM)分级系统,系统评价国内外最新循证医学证据,结合我国临床实际,针对痛风性关节炎/痛风石外科干预适应证、围手术期管理、术式选择及康复等8项关键临床问题,制定本专家共识,旨在提升临床决策的有效性、科学性和规范性.
Gout is a metabolic rheumatic disease characterized by hyperuricemia resulting from purine metabolism disor-ders and/or reduced uric acid excretion,leading to monosodium urate(MSU)crystal deposition and tissue damage.It can affect joints,causing gouty arthritis and significantly impairing patients'quality of life.Although urate-lowering drug ther-apy has played a significant role in managing gouty arthritis and tophi,surgical intervention is often required for severe structural damage,functional limitations,or refractory pain in soft tissues and/or joints caused by tophi that are unrespon-sive to conservative treatment.To systematically enhance the standardization of surgical diagnosis and treatment for gouty arthritis and tophi,the Beijing Society of Integrative Medicine initiated a collaborative effort led by Shanghai Guanghua Hospital of Integrated Traditional Chinese and Western Medicine and South China Hospital Affiliated to Shenzhen University.In partnership with the Institute for Joint Diseases,Shanghai Academy of Traditional Chinese Medicine,experts from rheumatology,joint surgery,and orthopedic departments at multiple Grade A tertiary hospitals nationwide were organized.Based on the Oxford Centre for Evidence-Based Medicine(OCEBM)grading system,this expert consen-sus addresses eight critical clinical issues,including indications for surgical intervention,perioperative management,surgi-cal technique selection,and rehabilitation by systematically evaluating the latest domestic and international evidence-based medical evidence and integrating China's clinical realities.It aims to enhance the effectiveness,scientific rigor,and stand-ardization of clinical decision-making.
肖涟波;杨功旭;金群华;接力刚;糜菁熠;何东仪;戴生明;陶金辉;戴号;沈军;程少丹;黄慈波;陈卫衡;雷光华;凌光辉;于杰;薛愉;卢启贵;许鹏
上海市光华中西医结合医院(上海,200052)||上海市中医药研究院关节病研究所湖北省中医院宁夏医科大学总医院南方医科大学珠江医院无锡市第九人民医院上海市光华中西医结合医院(上海,200052)||上海市中医药研究院关节病研究所上海市第六人民医院中国科学技术大学附属第一医院上海市光华中西医结合医院(上海,200052)||上海市中医药研究院关节病研究所上海市光华中西医结合医院(上海,200052)||上海市中医药研究院关节病研究所上海市光华中西医结合医院(上海,200052)||上海市中医药研究院关节病研究所深圳大学附属华南医院北京中医药大学附属第三医院中南大学湘雅医院中南大学湘雅二医院中国中医科学院望京医院复旦大学附属华山医院深圳市罗湖区中医院西安市儿童医院
医药卫生
痛风性关节炎痛风石外科诊疗专家共识
gouty arthritistophisurgerydiagnosis and treatmentexpert consensus
《中国中医骨伤科杂志》 2026 (2)
1-11,11
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