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家庭药师参与的咳喘药学监护应用效果评价OA

Evaluation of Application Effect of Pharmaceutical Care for Cough and Asthma Participated by Family Pharmacists

中文摘要英文摘要

目的 探讨家庭药师参与的咳喘药学监护服务对慢性阻塞性肺疾病(COPD)患者的干预效果.方法 选取医院 2024 年 1 月至10 月收治的COPD患者 100 例,按随机数字表法分为对照组和观察组,各 50 例.两组患者均接受常规诊疗模式干预,观察组患者在此基础上联合家庭药师参与的咳喘药学监护服务,共干预 6 个月.比较两组患者干预前后的肺功能、疾病控制情况和呼吸困难程度,满意度、药品不良反应(ADR)发生情况,以及用药依从性.结果 干预后,两组患者第 1 秒用力呼气容积(FEV1)占预测值百分比(FEV1%)、FEV1 与用力肺活量(FVC)比值均显著升高,疾病控制情况评分、呼吸困难程度评分均显著降低,满意度评分和用药依从性评分均显著升高(P<0.05),且观察组上述指标均显著优于对照组(P<0.05).观察组ADR发生率显著低于对照组(6.00%比20.00%,P<0.05).结论 家庭药师参与的咳喘药学监护服务可提高COPD患者的肺功能,有利于症状控制,降低呼吸困难程度,同时促进患者满意度和用药依从性的提升,且对ADR有一定预防作用.

Objective To investigate the intervention effect of pharmaceutical care for cough and asthma participated by family pharmacists on patients with chronic obstructive pulmonary disease(COPD).Methods A total of 100 COPD patients admitted to our hospital from January to October in 2024 were selected and divided into the control group and the observation group by the random number table method,with 50 cases in each group.Patients in both groups received conventional diagnostic and treatment interventions,and patients in the observation group additionally received pharmaceutical care services for cough and asthma participated by family pharmacists on this basis,a total intervention period of both groups were six months.Then,the pulmanary function,disease control,degree of dyspnea,satisfaction,incidence of adverse drug reaction(ADR),and medication compliance between the two groups before and after intervention were compared.Results After intervention,the percentage of forced expiratory volume in one second(FEV1)to predicted value(FEV1%),and the ratio of FEV1 to forced vital capacity(FVC)in both groups were significantly increased,the scores of disease control and degree of dyspnea in both groups were significantly decreased,and the scores of patients' satisfaction and medication compliance were significantly increased(P<0.05).Moreover,the above indicators in the observation group were significantly better than those in the control group(P<0.05).The incidence of ADR in the observation group were significantly lower than that in the control group(6.00%vs.20.00%,P<0.05).Conclusion Pharmaceutical care for cough and asthma participated by family pharmacists can improve the pulmonary function of COPD patients,help to control symptoms,reduce the degree of dyspnea,promote patients' satisfaction and medication compliance,and it has a certain preventive effect on ADRs.

谭燕萍;李玮炜;邵少勤

广东省佛山市禅城区人民医院,广东 佛山 528000广东省佛山市禅城区人民医院,广东 佛山 528000广东省佛山市禅城区人民医院,广东 佛山 528000

医药卫生

家庭药师慢性阻塞性肺疾病咳喘药学监护肺功能用药依从性药品不良反应

family pharmacistschronic obstructive pulmonary diseasecough and asthmapharmaceutical carepulmonary functionmedication complianceadverse drug reaction

《中国药业》 2026 (4)

143-148,6

广东省佛山市科学技术局科技创新项目[2320001006063].

10.3969/j.issn.1006-4931.2026.04.029

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