清下解胰颗粒早期干预轻中度急性胰腺炎患者的临床疗效OA
Clinical effects of early intervention of Qingxia Jieyi Granules on patients with mild-to-moderately acute pancreatitis
目的 考察清下解胰颗粒早期干预轻中度急性胰腺炎患者的临床疗效.方法 69 例患者随机分为对照组(34例)和观察组(35 例),对照组给予常规治疗,观察组在对照组基础上加用清下解胰颗粒,疗程 1 周.检测重症化发生率、器官功能障碍情况、改良Marshall评分、中医证候疗效和评分、血清生化指标(D-二聚体、C-反应蛋白、淀粉酶、脂肪酶)变化.结果 观察组中医证候总有效率高于对照组(P＜0.05),重症化发生率更低(P＜0.05).治疗后,2 组器官功能障碍情况改善(P＜0.05),改良Marshall评分、中医证候评分、血清生化指标降低(P＜0.05),以观察组更明显(P＜0.05).结论 清下解胰颗粒早期干预轻中度急性胰腺炎患者时,可截断其重症化.
AIM To investigate the clinical effects of early intervention of Qingxia Jieyi Granules on patients with mild-to-moderately acute pancreatitis.METHODS Sixty-nine patients were randomly assigned into control group(34 cases)for 1-week intervention of conventional treatment,and observation group(35 cases)for 1-week intervention of both Qingxia Jieyi Granules and conventional treatment.The changes in incidence of reanimation,organ dysfunction condition,modified Marshall score,TCM syndrome efficacy and score and serum biochemical indices(D-dimer,C-reactive protein,amylase,lipase)were detected.RESULTS The observation group demonstrated higher total effective rate of TCM syndromes than the control group(P＜0.05),along with lower incidence of reanimation(P＜0.05).After the treatment,the 2 groups displayed improved organ dysfunction condition(P＜0.05),and decreased modified Marshall score,TCM syndrome score and serum biochemical indices(P＜0.05),especially for the observation group(P＜0.05).CONCLUSION For the patients with mild-to-moderately acute pancreatitis,the early intervention of Qingxia Jieyi Granules can intercept its severity.
江雨洁;朱生樑;周秉舵;刘晓文;朱华芳;唐义爽;吴月;刘宇洋;张良;孔婧;王晓素
上海中医药大学附属岳阳中西医结合医院,上海 200437上海中医药大学附属岳阳中西医结合医院,上海 200437上海中医药大学附属岳阳中西医结合医院,上海 200437上海中医药大学附属岳阳中西医结合医院,上海 200437上海市黄浦区老年护理医院,上海 200010上海中医药大学附属岳阳中西医结合医院,上海 200437上海中医药大学附属岳阳中西医结合医院,上海 200437上海中医药大学附属岳阳中西医结合医院,上海 200437上海中医药大学附属岳阳中西医结合医院,上海 200437上海中医药大学附属岳阳中西医结合医院,上海 200437上海中医药大学附属岳阳中西医结合医院,上海 200437
医药卫生
清下解胰颗粒常规治疗轻中度急性胰腺炎早期干预重症化
Qingxia Jieyi Granulesconventional treatmentmild-to-moderately acute pancreatitisearly interventionseverity
《中成药》 2026 (1)
91-96,6
国家自然科学基金资助项目(81973809)上海市中西医临床协作试点建设项目(ZY2018-2020-FWTX-1004)上海市卫健委-上海市中医药高层次人才引领计划项目[ZY(2021-2023)-0403]上海市卫健委-中医药创新团队(2022CX002)中国中医科学院科技创新工程(CI2021A01001)
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