鼻腔鼻窦黏膜黑色素瘤诊疗专家共识(2025年版)OA

Sinonasal mucosal melanoma(SNMM)is a rare and highly aggressive malignant tumor originating from melanocytes,with a poor prognosis.Despite advancements in medical technology and treatment approaches in recent years,there remains a lack of standardized diagnostic and therapeutic guidelines for SNMM,as well as high-level evidence from clinical research globally.To standardize the clinical diagnosis and treatment process of SNMM,the Melanoma Multidisciplinary Team of Chongqing University Cancer Hospital the nominal group technique to develop an outline for consensus compilation.Based on the outline,the expert of writing group systematically retrieved and analyzed relevant domestic and foreign literature,and combined with actual clinical experience,initially drafted the recommendations.Subsequently,through the consensus formation conference,experts from the Special Committee on Rare and Intractable Diseases of Cancers of Chongqing Medical Biotechnology Association,and the Tumor Precision Treatment Committee of Chongqing Anti-Cancer Association evaluated the evidence,revised the recommendations,and finalized the consensus content and recommendation strengths through voting,and finally developed Expert Consensus on Diagnosis and Treatment of Sinonasal Mucosal Melanoma(2025 Edition).The consensus includes guidelines on SNMM epidemiology,diagnosis,treatment,and follow-up,aiming to provide standardized reference for clinical diagnosis and treatment.As higher-level evidence becomes available,this consensus will be continuously updated to further enhance the standardized management of SNMM.