基于"络病理论"探讨甲状腺相关眼病的病机特点OA

The thyroid gland,eyes,and collateral system are extensively interconnected.In"Collateral Disease Theory","Qi collaterals"and"blood collaterals"share functional unity with the thyroid in systemic regulation."Qi collaterals"exhibit similarities with the neuro-endocrine-immune(NEI)network,while"blood collaterals"align with the microcirculatory system,both reflected in the physiological functions and pathological changes of thyroid-associated ophthalmopathy(TAO).Based on theoretical and clinical research progresses on TAO,this paper proposes that"collateral deficiency with stasis-toxin stagnation"constitutes its core pathogenesis."Deficiency,stasis,and toxin"represent distinct pathological states in viscera and ocular blood collaterals,as well as key factors in its persistent and refractory nature.Additionally,the"Qi collateral-NEI"network governs the balance of Yin and Yang.Treatment should focus on harmonizing Yin and Yang.Guided by"Collateral Disease Theory",this study explores TAO's pathogenesis from the perspectives of"Qi collaterals"and"blood collaterals",providing novel theoretical insights and diagnostic approaches for clinical management.