脐针疗法、中药调周法联合盆底仿生物电刺激治疗薄型子宫内膜不孕症临床研究OA

Objective:To observe the clinical efficacy of combining umbilical acupuncture,menstrual cycle regulation with Chinese medicine,and pelvic floor biomimetic electrical stimulation in the treatment of thin endometrial infertility of kidney deficiency and liver stagnation type.Methods:A total of 120 patients with thin endometrial infertility of kidney deficiency and liver stagnation type admitted to Jiaxing Hospital of Traditional Chinese Medicine from January 2023 to November 2024 were enrolled and randomly divided into the control group and the observation group,with 60 cases in each group.The control group received Estradiol Tablets/Estradiol and Dydrogesterone Tablets,while the observation group received a combined therapy of umbilical acupuncture,menstrual cycle regulation with Chinese medicine,and pelvic floor biomimetic electrical stimulation.Both groups were treated for three menstrual cycles.Before and after treatment,traditional Chinese medicine syndrome scores were assessed,serum reproductive hormone levels[estradiol(E2),progesterone(P),follicle-stimulating hormone(FSH)],endometrial thickness,and uterine artery blood flow parameters[pulsatility index(PI),resistance index(RI)]were measured.The clinical efficacy of the two groups was compared.A six-month follow-up was conducted after treatment to compare the pregnancy success rates between the two groups.Results:After three menstrual cycles of treatment,the total effective rate in the observation group was 91.67%(55/60),significantly higher than that of 73.33%(44/60)in the control group(P＜0.05).Traditional Chinese medicine syndrome scores decreased in both groups compared with those before treatment(P＜0.05),with the observation group showing lower scores than the control group(P＜0.05).Serum E2 and P levels increased,while FSH levels decreased in both groups compared with those before treatment,with statistically significant differences(P＜0.05);and the observation group had higher serum E2 and P levels and lower FSH levels than the control group(P＜0.05).Endometrial thickness increased in both groups compared with that before treatment(P＜0.05),with the observation group showing greater thickness than the control group(P＜0.05).Uterine artery PI and RI values decreased in both groups compared with those before treatment(P＜0.05),with the observation group exhibiting lower values than the control group(P＜0.05).The pregnancy success rate in the observation group was 61.67%(37/60),significantly higher than that of 31.67%(19/60)in the control group(P＜0.05).Conclusion:The comprehensive therapy combining umbilical acupuncture,menstrual cycle regulation with Chinese medicine,and pelvic floor biomimetic electrical stimulation in the treatment of thin endometrial infertility of kidney deficiency and liver stagnation type can effectively improve traditional Chinese medicine syndromes,increase endometrial thickness,and improve pregnancy rates.The mechanism may involve regulating hormone secretion levels and promoting uterine blood circulation.