2025版NCCN葡萄膜黑色素瘤临床实践指南解读OA
Interpretation of the 2025 Guidelines for Uveal Melanoma by the National Comprehensive Cancer Network
葡萄膜黑色素瘤是一种好发于中老年人的眼内恶性肿瘤,早期症状隐匿,诊断需结合影像学检查.治疗策略因分期而异:早期患者常采用放射治疗或局部治疗以保留视力;晚期或转移患者则需结合手术、靶向及免疫治疗.本文基于2025年美国国家综合癌症网络(NCCN)更新的葡萄膜黑色素瘤临床实践指南,旨在解读该病的最新诊疗进展,为临床诊疗优化提供依据.
Uveal melanoma is an intraocular malignancy predominantly affecting middle-aged and elderly individuals.Its early symptoms are often subtle,necessitating imaging studies for diagnosis.Treatment strategies vary by stage:early-stage patients typically receive radiotherapy or local therapies to preserve vision,while advanced or metastatic cases require combined approaches including surgery,targeted therapy,and immunotherapy.Based on the 2025 update of the Guidelines for Uveal Melanoma by the National Comprehensive Cancer Network,this article aims to interpret the latest advances in the diagnosis and treatment of this disease,providing a basis for the optimization of clinical diagnosis and treatment.
邵毅;刘湘艺;王怡欣
200080 上海市,上海交通大学医学院附属第一人民医院眼科中心330006 江西省南昌市,南昌大学第一附属医院眼科CF244HQ 威尔士卡迪夫市,英国卡迪夫大学眼科学与视觉科学系
医药卫生
葡萄膜黑色素瘤危险因素诊断治疗
uveal melanomarisk factorsdiagnosistreatment
《眼科新进展》 2026 (2)
85-90,6
国家自然科学基金项目(编号:82160195,82460203)
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