1 454例女性HPV感染基因型分析OA

Objective To analyze the infection status and genotyping of Human Papilloma vi-rus(HPV)in women in Shantou City,Guangdong Province,and to provide scientific evidence for the local HPV vaccination strategy.Methods A retrospective analysis was performed on the data of 8 780 female patients underwent HPV testing in Shantou City between 2022 and 2024.The overall HPV infection rate,distribution of HPV genotypes,and age-specific characteristics of in-fection were analyzed.Results Out of 8 780 patients,1 454 tested positive,and the HPV infec-tion rate was 16.56%,with notably elevated rates in those aged 31-40 years and 41-50 years.Single high-risk genotypes accounted for the majority of infection cases.The top nine HPV geno-types identified included seven high-risk types and two low-risk types,namely:HPV 52(17.42%),HPV 16(6.55%),HPV 53(6.55%),HPV 51(5.59%),HPV 58(5.55%),HPV 68(5.18%),HPV 18(4.40%),as well as HPV 81(6.42%)and HPV 43(4.03%).Conclusions The HPV infection rate among women in Shantou is basically close to the overall level of women in mainland China.Sexually active women are the high-risk population for HPV in-fection.The 9-valent HPV vaccine has not been able to widely cover the susceptible HPV genetic subtypes in this region.