中药材莪术的镉污染吸收蓄积规律及镉污染防控措施的研究进展OA

Curcuma zedoaria(commonly known as"E Zhu"in traditional Chinese medicine)is a perennial herb,and its rhizome is used for medical purpose.It is clinically effective for treating various symptoms caused by blood stasis.For oral administration,E Zhu is often combinded with other traditional Chinese medicines to prepare various formulations such as decoctions,pills,and tablets.This allows its medicinal properties to reach the internal organs and meridians,promotes the flow of qi and blood,and dissipates stasis and stagnation.E Zhu is mainly distributed in Guangxi,Sichuan,Zhejiang,Yunnan,and other regions in China.However,cadmium(Cd)con-tamination has emerged in multiple areas due to the development of battery,smelting,electro-plating,and chemical industries.Additionally,the intrinsic Cd-accumulation property of E Zhu coupled with the Cd pollution has rendered a prominent issue during its cultivation and medicinal application,thereby comprimising the safety and efficacy of its clinical use.This paper compre-hensively reviewed the absorption and accumulation patterns of Cd in E Zhu and proposed a comprehensive chain of control measures from cultivation to processing and purification,aiming to reduce Cd in E Zhu.These measures are expected to lower the potential risk of low-dose Cd accumulation in the human body and further ensure the safe clinical application of E Zhu as a raw material in traditional Chinese medicine.