脂肪组织与多器官交互调控的研究进展OA

Adipose tissue,a vital component of the human body,serves multiple functions,including energy storage,thermal insulation,and protection.Fat is a highly active,dynamic organ that communicates with other organs,playing a crucial role in maintaining health and is closely linked to the onset and progression of diseases.Chronic diseases associated with adipose tissue result from dysregulated inter-organ interactions and have become a major public health challenge.A systematic review of regulatory networks centered on adipose tissue could help overcome the limitations of single-organ studies and identify key inter-organ communication pathways.This article reviews recent advances regarding adipose tissue as a pivotal signaling hub that facilitates inter-organ communication with the liver,gut,brain,and bone,as well as its connection to tumor progression.The review also highlights the applications of cutting-edge technologies such as single-cell sequencing and artificial intelligence in adipose tissue research.Continued exploration of the crosstalk between adipose tissue and other organs holds great potential for disease treatment and health management.