老年住院患者衰弱与慢性疾病及血脂水平的相关性研究OA
Correlation between frailty with chronic diseases and blood lipid level in elderly inpatients
目的 分析老年住院患者衰弱与慢性疾病、血脂水平的关系.方法 选取2022年1月至2024年1月该院收治的年龄≥60岁的住院患者为研究对象,根据衰弱情况分为衰弱组(n=243)和衰弱前期组(n=212),选取同期老年住院无衰弱患者为对照组(n=97).采用一般资料调查、FRAIL衰弱量表和慢性疾病调查表收集资料,单因素和多因素logistic回归分析影响因素.结果 3组性别、年龄、TC、HDL-C、LDL-C、载脂蛋白A(apoA)、载脂蛋白B(apoB)水平、高血压病、冠心病、肾功能不全、心力衰竭、慢性阻塞性肺疾病、呼吸衰竭、痴呆发生率比较差异有统计学意义(P<0.05).多因素logistic回归分析显示,年龄大、呼吸衰竭、痴呆是衰弱的独立危险因素(P<0.05),apoA(P3)是保护因素(P=0.022);仅年龄是衰弱前期的影响因素(P<0.05).结论 老年住院患者衰弱受年龄、呼吸衰竭、痴呆及血脂水平等因素影响,其可作为病情评估的监测指标.
Objective To analyze the relationship between the frailty in elderly inpatients with chronic diseases and blood lipid levels.Methods The inpatients aged≥60 years old in this hospital from January 2022 to January 2024 were selected as the study subjects and divided into the frailty group(n=243)and frailty pro-phase group(n=212)according to the frailty condition.The elderly inpatients without frailty during the same period served as the control group(n=97).The general data investigation,FRAIL scale and chronic disease questionnaire were adopted to collect the data.The univariate and multivariate Logistic regression were used to analyze the influencing factors.Results The sex,age,total cholesterol(TC),high-density lipoprotein cho-lesterol(HDL-C),low-density lipoprotein cholesterol(LDL-C),apolipoprotein A(apoA),apoB,hyperten-sion,c oronary heart disease,renal insufficiency,heart failure,chronic obstructive pulmonary disease,respira-tory failure and dementia had statistical differences among 3 groups(P<0.05).The multivariate logistic re-gression analysis indicated that the old age,respiratory failure and dementia were the independent risk factors for frailty(P<0.05),while apoA(P3)was the independent protective factor(P=0.022).Only age was the influencing factor of frailty prophase(P<0.05).Conclusion Frailty in elderly inpatients is affected by the age,respiratory failure,dementia and blood lipid levels.These factors could serve as the monitoring indicators for assessing the disease condition.
李宝善;林秋梅;唐杨洋;蒋宜;王兴胜
重庆市急救医疗中心/重庆市第四人民医院:老年病科,重庆 400014重庆市急救医疗中心/重庆市第四人民医院:全科医学科,重庆 400014重庆市急救医疗中心/重庆市第四人民医院:老年病科,重庆 400014重庆市急救医疗中心/重庆市第四人民医院:全科医学科,重庆 400014重庆市急救医疗中心/重庆市第四人民医院:老年病科,重庆 400014
医药卫生
老年人衰弱危险因素慢性疾病血脂
elderlyfrailtyrisk factorschronic diseasesblood lipid
《重庆医学》 2026 (1)
67-74,8
重庆市技术创新与应用发展专项重点项目(CSTB2022TIAD-KPX0188).
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