重组人粒细胞集落刺激因子临床应用管理中国专家共识(2026版)OA
Chinese Expert Consensus on Clinical Application and Management of Recombinant Human Granulocyte-Colony Stimulating Factor(2026 Edition)
中性粒细胞减少症是抗肿瘤治疗中常见的血液学毒性事件,可导致治疗延迟和剂量减低,严重时可引起中性粒细胞减少性发热(FN),影响患者预后.人粒细胞集落刺激因子(G-CSF)已被广泛应用于治疗中性粒细胞减少症,可实现疾病的早期预防,降低FN发生,提高抗肿瘤疗效.但当前G-CSF在临床应用中的规范化仍需提升,肿瘤药师在药物规范化应用中占据重要地位.基于此,中国抗癌协会整合肿瘤药学委员会联合多个专业委员会制定本共识,旨在优化G-CSF的应用,降低医疗成本,做好G-CSF药物监护,提升患者获益.
Neutropenia is a common hematologic toxicity during antitumor therapy and can induce treatment delays,dose reduction,and even febrile neutropenia(FN),thereby causing poor prognosis.Human granulocyte-colony stimulating factor(G-CSF)has been widely used in the treatment of neutropenia,enabling early disease prevention,reduction in FN incidence,and improvement in antitumor efficacy.However,the standardization of G-CSF in clinical application still needs to be enhanced,and oncology pharmacists play a crucial role in its standardized application.Together with multiple professional committees,the Chinese Anti-Cancer Association Integrated Oncology Pharmacy Committee has developed the consensus to optimize G-CSF application,reduce medical costs,improve G-CSF pharmaceutical monitoring,and enhance patient benefits.
中国抗癌协会整合肿瘤药学委员会;中国抗癌协会肿瘤内科学专业委员会;董梅;沈波
哈尔滨医科大学附属肿瘤医院||中国抗癌协会整合肿瘤药学委员会江苏省肿瘤医院||中国抗癌协会肿瘤内科学专业委员会
医药卫生
人粒细胞集落刺激因子中性粒细胞减少症恶性肿瘤临床应用
Human granulocyte-colony stimulating factorNeutropeniaMalignant tumorsClinical application
《肿瘤防治研究》 2026 (1)
1-16,16
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