二元Logistic回归分析二尖瓣关闭不全患者冠脉搭桥术后发生低氧血症的相关因素OA

Objective To identify factors associated with postoperative hypoxemia after coronary artery bypass grafting(CABG)in patients with mitral regurgitation(MR)using binary logistic regression analysis.thereby providing evidence for early development of targeted interventions and reduction of hypoxemia risk.Methods This retrospective study included 200 patients with MR who underwent CABG in our hospital from May 2021 to May 2025.According to whether postoperative hypoxemia occurred.patients were assigned to the hypoxemia group(n=56)or the non-hypoxemia group(n=144).Clinical characteristics were compared between the two groups.Binary logistic regression analysis was performed to determine factors associated with postoperative hypoxemia in MR patients after CABG.Results Preoperative left ventricular ejection fraction(LVEF)in the hypoxemia group was significantly lower than that in the non-hypoxemia group(P＜0.05).Moreover.the proportions of cardiopulmonary bypass(CPB)time＞120 min.intraoperative fluid overload.absence of lung-protective ventilation.a history of smoking.and inadequate postoperative analgesia were significantly higher in the hypoxemia group than in the non-hypoxemia group(P＜0.05).Binary logistic regression analysis showed that CPB time＞120 min.intraoperative fluid overload.absence of lung-protective ventilation.a history of smoking.and inadequate postoperative analgesia were factors associated with postoperative hypoxemia in MR patients after CABG(P＜0.05).Conclusion CPB time＞120 min.intraoperative fluid overload.absence of lung-protective ventilation.a history of smoking.and inadequate postoperative analgesia are associated factors for postoperative hypoxemia after CABG in patients with MR.These findings provide a reference for clinical risk assessment of postoperative hypoxemia and for developing corresponding intervention strategies.