m6A修饰调控miRNAs影响细胞能量代谢的研究进展OA

N6-methyladenosine(m6A)modification and microRNAs(miRNAs)are important factors in gene expression regulation,playing a crucial role in cellular energy metabolism.m6A modification participates in various physiological and pathological processes by regulating RNA stability,splicing and translation.miRNAs,as a class of small molecule RNAs,directly affect cellular metabolic pathways by targeting and regulating gene expression.The m6A modification-mediated regulation of miRNAs plays a pivotal role in cellular energy metabolism,especially in regulating metabolic processes such as glycolysis and mitochondrial function.By discussing the regulatory effect of m6A modification on miRNAs and its impact on energy metabolism,this review elaborating in detail on the mechanism by which m6A modification affects cellular energy metabolism by regulating miRNAs,and reveals the possibility of m6A modified miRNAs as targets for regulating cellular energy metabolism,in order to provide a theoretical reference for regulating animal growth and development and treating energy metabolism-related diseases.