错(牙合)患者正畸后切牙炎症相关牙根吸收风险因素及基于锥形束CT的预测模型构建OA

Objective To analyze the risk factors of root resorption related to inflammation of incisors in patients with maloc-clusion after orthodontic treatment and to construct a risk prediction model based on cone-beam CT(CBCT).Methods A total of 110 patients(including 401 maxillary incisors)who underwent orthodontic treatment for malocclusion in the Department of Stomatology of the 904th Hospital of PLA Joint Logistics Support Force from January 2018 to January 2023 were retrospectively included,and were di-vided into severe resorption and non-severe resorption groups based on the presence or absence of root resorption associated with inflam-mation of the incisors during the follow-up period after the treatment.All the patients were treated with conventional orthodontic weigh-ting,and fixed orthodontics or invisibles were used according to the degree of malocclusion.The data of patients were collected,which were analyzed by binary logistic regression analysis and subject work characteristic curves(ROC).Results Eighty-four incisors with inflammation-related root resorption occurred during the follow-up period after treatment of 401 maxillary incisors in 110 patients,with an incidence rate of 20.95%.The results of univariate analysis showed that age at initial consultation,treatment time,pre-treatment root length and length of root movement in the vertical direction were associated with inflammation-related root resorption of incisors af-ter orthodontic treatment in patients with malocclusion(P<0.05).The binary logistic regression analysis showed that the initial diagno-sis age(OR=1.327,95%CI:1.191-1.477,P=0.000),and treatment period(OR=1.003,95%CI:1.000-1.005,P=0.008)were the independent risk factors for the risk of inflammation-associated root resorption of post-orthodontic incisors,while the pre-treat-ment root length(OR=0.285,95%CI:0.204-0.397,P=0.000),and length of root movement in the vertical direction(OR=0.114,95%CI:0.052-0.251,P=0.003)were independent protective fac-tors for the risk of developing root resorption associated with inflammation of post-orthodontic incisors.The AUC of the initial diagnosis age for predicting inflammation-related root resorption of post-orthodontic incisors in patients with malocclusion was 0.768(0.700-0.836),the AUC for the treatment period was 0.633(0.561-0.704),the AUC for the length of the roots before treatment was 0.874(0.839-0.910),and the AUC for the length of the roots moving in the vertical direction was 0.799(0.754-0.843).The Yoden in-dex was 0.519,and the optimal cutoff value was 0.62.Conclusions Root resorption associated with inflammation of the incisors in patients after orthodontic treatment is closely related to the initial diagnosis age,duration of treatment,pre-treatment root length and length of root movement in the vertical direction,with good diagnostic efficacy of age at initial consultation,pre-treatment root length,and length of root movement in the vertical direction as predictors.