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从厥阴病辨治胃癌前病变的思路OA

Differentiation and treatment ideas for gastric precancerous lesions from the perspective of jueyin diseases

中文摘要英文摘要

慢性萎缩性胃炎伴肠上皮化生和/或不典型增生是胃癌前病变(precancerous lesion of gastric cancer,PLGC).厥阴为两阴交尽、三阴之里,其脏腑为多血少气之脏.厥阴病为阴尽阳生失调,机体出现寒热错杂、上热下寒,总体以虚、寒为本,实、热为标.PLGC本质为阴阳不接、气血失阖.虚证是PLGC基本证型,PLGC中后期虚实、寒热错杂特征突出.PLGC病起于脾土阳虚、肝寒失阖,病进于相火郁扰、痰湿酿热,病变于初阳不生、寒热失燮.恢复厥阴阴尽阳生平衡为PLGC主要治法,具体包括:升降气机,中调寒热;通阳破阴,制用护体;不拘一格,灵活变通.并结合临床验案阐述从厥阴病辨治PLGC的思路.

Chronic atrophic gastritis with intestinal metaplasia and/or atypical hyperplasia is a precancerous lesion of gastric cancer(PLGC).Jueyin meridian is the intersection of two yin meridians and the interior of the three yin meridians,and its corresponding zang-fu organs are characterized by being rich in blood but deficient in qi.Jueyin Diseases are characterized by the imbalance of yin and yang,leading to a complex pattern of cold and heat,with cold in the lower part and heat in the upper part.The overall condition is fundamentally deficient and cold,with manifestations of excess and heat as secondary features.The essence of PLGC is the disconnection of yin and yang and the loss of harmony in qi and blood.Deficiency patterns are the basic pattern of PLGC,and the characteristics of intermingled deficiency and excess,as well as cold and heat,are prominent in the middle and late stages of PLGC.The condition originates from the deficiency of spleen yang and the failure of liver cold to close,progresses with the disturbance of ministerial fire and the generation of phlegm-dampness and heat,and manifests as the failure of initial yang to arise and the loss of coordination between cold and heat.Restoring the balance of yin and yang in jueyin is the main treatment method for PLGC,which specifically includes:restoring the ascending and descending of qi,harmonizing cold and heat in the middle;promoting yang and breaking yin,protecting the body while using restraints;and being flexible and adaptable without being bound by one fixed mode.The approach to treating precancerous lesions of gastric cancer from the perspective of jueyin diseases is illustrated with clinical cases.

于婧杰;冯利;沈洋;侯丽;李潇;吕丽媛;齐宇镈;张宇;史敏慧

北京中医药大学东直门医院 北京 100700国家癌症中心/国家肿瘤临床医学研究中心/中国医学科学院肿瘤医院中医科北京中医药大学东直门医院 北京 100700北京中医药大学东直门医院 北京 100700北京中医药大学东直门医院 北京 100700北京中医药大学东直门医院 北京 100700北京中医药大学东直门医院 北京 100700北京中医药大学东直门医院 北京 100700北京中医药大学东直门医院 北京 100700

医药卫生

厥阴病伤寒论胃癌前病变辨治

jueyin diseaseTreatise on Cold Damage Diseasesprecancerous lesion of gastric cancerdiagnosis and treatment

《现代中医临床》 2026 (1)

49-53,5

中国中医科学院西苑医院提升中医药临床循证证据级别研究专项(No.XYZX0201-19)北京中医药大学东直门医院临床研究和成果转化能力提升试点项目(No.DZMG-ZLZX-25018)

10.3969/j.issn.2095-6606.2026.01.009

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