基于肝脾同调理论探讨体复康治疗中枢疲劳的机理OA
Exploring the mechanism of Tifukang in treating central fatigue based on the theory of simultaneous regulation of liver and spleen
中枢疲劳是指由于长期精神压力等原因引起中枢神经系统病变,从而引发疲倦感加重、认知功能降低、动机降低等生理和心理上的过程,目前尚无特效的治疗手段."体复康"为杨维益教授的抗疲劳经验方,对中枢疲劳的疗效较好,但其治疗中枢疲劳的机理尚不明确.本文从体复康中药复方的组方规律入手,结合现代药理研究成果,以肝脾同调理论为基础,参合中枢疲劳肝失疏泄、脾失健运的关键病机,探讨本方治疗中枢疲劳的中医机理,为针对体复康治疗中枢疲劳的相关基础及临床研究提供理论依据,以期为中枢疲劳的临床诊疗方案开拓新的思路.
Central fatigue refers to a physiological and psychological process caused by long-term mental stress and other causes of central nervous system disease,which leads to increased fatigue,reduced cognitive function,and reduced motivation.Currently,there are no specific effective treatments.Tifukang is Professor Yang Weiyi's empirical formula for combating fatigue and has shown good efficacy against central fatigue,but its mechanism of treating central fatigue is still unclear.In this paper,starting from the composition principles of the Tifukang Chinese herbal compound,and integrating the result of modern pharmacological research,this paper explores the mechanism of this formula in treating central fatigue from the perspective of Traditional Chinese Medicine,based on the theory of simultaneous regulation of the liver and spleen,and referencing the key pathogenesis of central fatigue involving liver disharmony leading to impaired conveyance and dispersion,and spleen disharmony leading to impaired transportation and transformation.The aim is to provide a theoretical basis for fundamental and clinical research on Tifukang for treating central fatigue,and to potentially open new avenues for the diagnosis and treatment of central fatigue.
张翼飞;于清茜;兰碧娟;施晴寰;张泽涵;李峰
北京中医药大学中医学院 北京 102488北京中医药大学中医学院 北京 102488北京中医药大学中医学院 北京 102488北京中医药大学中医学院 北京 102488北京中医药大学中医学院 北京 102488北京中医药大学中医学院 北京 102488
医药卫生
中枢疲劳肝脾同调肝郁脾虚体复康中药复方
central fatiguesimultaneous regulation of the liver and spleenliver depression and spleen deficiencyTifukangTCM herbal compound formula
《现代中医临床》 2026 (1)
33-38,6
国家自然科学基金项目(No.81874428)国家自然科学基金青年项目(No.82204978)
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