537例超重/肥胖患者中医证素特征和证候分布规律的横断面研究OA

Objective To explore the distribution of TCM patterns in overweight/obese patients,and to provide reference for standardised diagnosis and clinical treatment.Methods A cross-sectional study method was used to collect information on the general conditions and TCM symptoms of overweight/obese patients attending the Beijing Hospital of Traditional Chinese Medicine,and descriptive statistics were performed.Factor analysis and cluster analysis were used to perform non-linear dimensionality reduction analysis to summarise the distribution of major TCM patterns.Results A total of 537 overweight/obese patients were included,including 118(21.97％)males and 419(78.03％)females,with an average age of(39.32±11.32)years and an average BMI of(29.65±3.97)kg/m2.The symptoms that appeared more frequently in them were lassitude and disinclination to speak or move,thirst with desire to drink,and abdominal fullness,and the disease location elements were mainly the spleen,stomach,and liver,and the disease nature elements were mainly qi stagnation,qi deficiency,and dampness;the TCM pattern types were mainly classified into stomach-intestine dampness-heat(18.44％),qi depression transforming into fire(13.78％),spleen deficiency dampness obstruction(48.60％),and spleen-kidney yang deficiency(19.18％).The analysis of overweight and obese patients showed that overweight patients'disease location elements were mainly the spleen,stomach and liver,and their disease nature elements were mainly qi stagnation,heat and dampness;their TCM patterns were mainly classified into qi depression transforming into fire(41.23％),spleen deficiency and dampness obstruction(31.58％),stomach-intestine dampness-heat(24.88％),and spleen and kidney yang deficiency(4.78％).In obese patients,the disease location elements were mainly the spleen,stomach and kidney,and the dissese nature elements were mainly qi deficiency,heat and qi stagnation;the TCM pattern elements were mainly classified into spleen deficiency and dampness obstruction(55.19％),stomach dampness and heat(19.81％),spleen and kidney yang deficiency(14.29％),and qi stagnation transforming into fire(11.04％).Conclusions The pathogenesis of overweight/obesity in TCM involves a complex intermingling of deficiency and excess.The main syndrome types are stomach-intestine dampness-heat,qi depression transforming into fire,spleen deficiency dampness obstruction and spleen-kidney yang deficiency.Furthermore,as BMI increases,a changing pattern is observed,shifting from predominantly excess patterns initially to more deficiency patterns later.