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中医药多维干预绝经后骨质疏松症OA

Traditional Chinese Medicine's Multidimensional Management of Postmenopausal Osteoporosis

中文摘要英文摘要

绝经后骨质疏松症(postmenopausal osteoporosis,PMOP)是一种由绝经期女性雌激素水平下降引发的骨代谢异常性疾病,其特征表现为骨密度降低、骨微结构破坏及骨骼脆性增加.现代医学药物(如激素替代疗法)虽然在改善骨代谢指标方面疗效显著,但长期应用可能导致不良反应,且治疗成本较高.基于"肾主骨生髓""脾主运化"的中医理论,通过药物干预、非药物疗法及生活方式管理等多维策略,在PMOP防治中展现出独特优势.系统梳理了其基础研究机制与临床应用成果,结合经典理论与现代实践,重点阐释了中药调控骨代谢信号通路、针灸改善骨骼微环境、中药熏蒸促进局部循环的作用机制,最终提出整合中药复方、物理疗法及运动生活方式管理的综合干预策略,以期为中医药防治PMOP提供更全面、科学的理论依据.

Postmenopausal osteoporosis(PMOP)is a bone metabolism disorder caused by a decrease in estrogen levels in menopausal women,characterized by decreased bone density,microstructural damage,and increased bone fragility.Although modern medical drugs,such as hormone replacement therapy,have significant therapeutic effects in improving bone metabolism indicators,long-term use may lead to adverse reactions and higher treatment costs.Based on the traditional Chinese medicine theories of"kidney governs bone and generates marrow"and"spleen governs transportation and transformation",traditional Chinese medicine has demonstrated unique advantages in the prevention and treatment of PMOP through multidimensional strategies such as drug intervention,non drug therapy,and lifestyle management.Systematically combed the basic research mechanism and clinical application results,combined with classical theory and modern practice,the mechanism of Chinese medicine regulating bone metabolism signal pathway,acupuncture and moxibustion improving bone microenvironment,and Chinese medicine fumigation promoting local circulation was emphatically explained.Ultimately,a comprehensive intervention strategy integrating traditional Chinese medicine formulas,physical therapy,and exercise lifestyle management is proposed to provide a more comprehensive and scientific theoretical basis for the prevention and treatment of PMOP with traditional Chinese medicine.

王铭洋;于冬冬

辽宁中医药大学,辽宁 沈阳 110847辽宁中医药大学附属医院,辽宁 沈阳 110032

医药卫生

中医药绝经后骨质疏松症多维干预经典理论现代实践

traditional Chinese medicinepostmenopausal osteoporosismultidimensional interventionclassical theorymodern practice

《中西医结合慢性病杂志》 2026 (1)

49-54,6

国家自然科学基金面上项目(82374480)

10.26950/j.issn.2097-5031.2026.01.007

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