首页|期刊导航|中西医结合肝病杂志|陈斌教授从肝脾论治自身免疫性肝病相关性贫血的经验

陈斌教授从肝脾论治自身免疫性肝病相关性贫血的经验OA

Professor Chen Bin's experience in treating autoimmune liver disease-associated anemia from the liver-spleen perspective

中文摘要英文摘要

脾胃为后天之本,气血生化之源,气血的化生与脾脏的运化功能密切相关.自身免疫性肝病(AILD)在疾病发生发展过程中可出现贫血,此乃AILD的肝外表现之一.陈斌教授基于20 年血液病临证经验,提出本病核心病机为"肝郁脾虚,湿热瘀毒互结,气血亏虚",病位虽在肝,但其本在脾.临证强调"肝脾同治",以"扶正祛邪,标本兼顾"为原则,治疗上首重"培土固本",即健脾益气以资气血化生之源,同时兼以疏肝解郁、清热利湿、化瘀解毒之法以祛其标实,临床疗效显著,充分体现了中医整体辨证与肝脾同调的优势.本文总结其诊疗经验,并附验案一则,以资借鉴.

The spleen and stomach are regarded as the foundation of postnatal life and the source of qi and blood production,as the generation of qi and blood is closely associated with the spleen's transforming and transporting functions.Anemia may arise during the course of autoimmune liver disease(AILD),which is one of its extrahepatic manifestations.Based on twenty years of clinical experience in hematological conditions,professor Chen Bin proposes that the core pathogenesis of this disease involves"liver depression and spleen deficiency,mutual binding of damp-heat and stasis-toxin,and deficiency of qi and blood".Although the disease location is in the liver,its root lies in the spleen.In clinical practice,he emphasizes"simultaneous treatment of the liver and spleen",guided by the principle of"supp orting healthy qi and eliminating pathogenic factors while addressing both the root and the branch".The therapeutic approach prioritizes"reinforcing the earth to strengthen the root"that is,fortifying the spleen and supplementing qi to enhance the source of qi and blood generation-while also incorporating methods to soothe the liver and relieve stagnation,clear heat and drain dampness,and dissolve stasis and remove toxins,thereby tackling the secondary manifestations.Significant clinical efficacy has been observed,fully demonstrating the advantage of holistic pattern differentiation and coordinated regulation of the liver and spleen in traditional Chinese medicine.This article summarizes Professor Chen's diagnosis and treatment experience,accompanied by a validated case example for reference.

曹小雄;许晶;冯兵兵;李惠平;陈斌

湖北省中医院(湖北 武汉,430061)中医肝肾研究及应用湖北省重点实验室,湖北中医药大学附属医院湖北时珍实验室湖北中医药研究院湖北省中医院(湖北 武汉,430061)

医药卫生

自身免疫性肝病贫血肝脾临证经验

autoimmune liver diseasesanemialiver-spleenclinical experience

《中西医结合肝病杂志》 2026 (1)

93-96,4

湖北省中医药管理局中医药科研项目(No.ZY2025L257)

10.3969/j.issn.1005-0264.2026.001.020

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