选择性消化道去污染辅助治疗CRKP所致持续性血流感染1例OA

Objective To provide reference for clinical diagnosis and treatment of persistent bloodstream infection caused by carbapenem-resistant Klebsiella pneumoniae(CRKP).Methods This paper reports the anti-infection treatment process of a patient with persistent bloodstream infection caused by CRKP.Clinical pharmacists partici-pated in the development of selective digestive decontamination(SDD)scheme to assist anti-infection,therapeutic efficacy was monitored and long-term follow-up after discharge was conducted.Results after SDD adjuvant treat-ment,patient's blood culture turned negative,condition was improved,and he was discharged from hospital.Six-month follow-up showed that the patient recovered well.Conclusion SDD adjuvant treatment may have therapeutic value for persistent bloodstream infection originating from the digestive tract,which is helpful to control the infec-tion of such patient.