首页|期刊导航|中国肛肠病杂志|经肛全直肠系膜切除术联合丁酸盐灌肠促进直肠癌患者术后肠道功能恢复的效果观察

经肛全直肠系膜切除术联合丁酸盐灌肠促进直肠癌患者术后肠道功能恢复的效果观察OA

Effect of Transanal Total Mesorectal Excision Combined with Butyrate Enema on Promoting Postopera-tive Intestinal Function Recovery in Patients with Rectal Cancer

中文摘要英文摘要

目的:观察经肛全直肠系膜切除术联合丁酸盐灌肠促进直肠癌患者术后肠道功能恢复的效果.方法:将我院2018年7月至2025年2月收治的直肠癌患者100例随机分为对照组和观察组,每组50例.对照组患者予以腹腔镜全直肠系膜切除术+术后常规对症治疗,观察组患者予以经肛全直肠系膜切除术+术后常规对症治疗+丁酸盐灌肠治疗,比较2组患者肠道功能、腹痛及腹胀情况以及胃肠激素水平.结果:观察组患者术后首次排气时间、首次排便时间均短于对照组(P<0.05).术后3 d、7 d观察组患者腹痛及腹胀评分均低于对照组(P<0.05).术后观察组患者胃动素(MOT)、胃泌素(GAS)水平均高于对照组(P<0.05).结论:经肛全直肠系膜切除术联合丁酸盐灌肠治疗直肠癌可减轻患者腹痛、腹胀症状,改善胃肠激素水平,促进肠道功能恢复.

Objective To observe the effect of transanal total mesorectal excision combined with butyrate enema on promoting postoperative intestinal function recovery in patients with rectal cancer.Methods A total of 100 patients with rectal cancer admitted to our hospital from July 2022 to February 2025 were randomly divided into a control group and an observation group,with 50 cases in each group.Patients in the control group were given laparoscopic total mesorectal excision and routine symptomatic treatment after surgery,while patients in the observation group were given transanal total mesorectal excision,routine symptomatic treatment after surgery and butyrate enema treatment.The intestinal function,abdominal pain and distension,and levels of gastrointestinal hormones of the two groups of patients were compared.Results The time of first exhaust and first defecation after surgery in the observation group were shorter than those in the control group(P<0.05).The scores of abdominal pain and distension in the observation group were lower than those in the con‐trol group on the 3rd and 7th days after surgery(P<0.05).The levels of motilin(MOT)and gastrin(GAS)in the observation group were higher than those in the control group after surgery(P<0.05).Conclusion Transanal total mesorectal excision combined with butyrate enema in the treatment of rectal cancer can relieve the symptoms of abdominal pain and distension,improve the levels of gastrointestinal hormones,and promote the recovery of intestinal function.

付建峰;肖元廷;王立军;孙会群

天津市天津医院(天津 300211)天津市天津医院(天津 300211)天津市天津医院(天津 300211)天津市天津医院(天津 300211)

直肠癌经肛全直肠系膜切除术丁酸盐灌肠肠道功能

Rectal cancerTransanal total mesorectal excisionButyrate enemaIntestinal function

《中国肛肠病杂志》 2026 (1)

14-16,3

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