厚朴七物汤联合新斯的明穴位注射对腹部术后早期炎性肠梗阻的效果观察OA
Clinical Efficacy of Houpo Qiwu Decoction Combined with Neostigmine Acupoint Injection in Treatment of Early Postoperative Inflammatory Ileus
目的:观察厚朴七物汤联合新斯的明穴位注射对腹部术后早期炎性肠梗阻的效果.方法:将我院2023年3月至2025年3月收治的腹部术后早期炎性肠梗阻患者随机分为对照组和观察组,每组30例.对照组患者采用常规对症治疗(胃肠减压、肠外营养支持、抗感染、补液、生长抑素等),观察组患者在此基础上予以厚朴七物汤联合新斯的明穴位注射治疗,比较2组患者的临床疗效、临床症状改善时间、炎症因子水平以及肠屏障功能.结果:观察组患者临床总有效率高于对照组(P<0.05).观察组患者腹胀消退时间、腹痛消退时间、恶心呕吐消退时间、肠鸣音恢复时间、肛门排气时间均短于对照组(P<0.05).治疗前2组患者炎症因子水平比较差异无统计学意义(P>0.05),治疗1周观察组患者C反应蛋白(CRP)、白细胞介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)水平均低于对照组(P<0.05).治疗前2组患者肠屏障功能指标比较差异无统计学意义(P>0.05),治疗1周观察组患者血清D-乳酸(D-LA)、内毒素(ET)、二胺氧化酶(DAO)水平均低于对照组(P<0.05).结论:腹部术后早期炎性肠梗阻采取厚朴七物汤联合新斯的明穴位注射具有显著的临床效果,可明显改善患者的临床症状,减轻炎症反应,调节肠屏障功能.
Objective To observe the clinical efficacy of Houpo Qiwu Decoction combined with neostig‐mine acupoint injection in the treatment of early postoperative inflammatory ileus(EPII).Methods A total of 60 patients with EPII admitted to our hospital from March 2023 to March 2025 were randomly divided into a control group and an observation group,with 30 cases in each group.The control group was treated with rou‐tine symptomatic therapy(including gastrointestinal decompression,parenteral nutrition support,anti-infection treatment,fluid replacement,somatostatin administration,etc.).On this basis,the observation group was additionally given Houpo Qiwu Decoction combined with neostigmine acupoint injection.The clinical efficacy,symptom improvement time,levels of inflammatory factors and intestinal barrier function were compared between the two groups.Results The total clinical effective rate of the observation group was significantly higher than that of the control group(P<0.05).The resolution time of abdominal distension and abdominal pain,disappearance time of nausea and vomiting,recovery time of bowel sounds,and time to first flatus in the observation group were all shorter than those in the control group(P<0.05).There was no statistically signifi‐cant difference in the levels of inflammatory factors between the two groups before treatment(P>0.05).After 1 week of treatment,the levels of C-reactive protein(CRP),interleukin-6(IL-6)and tumor necrosis factor-α(TNF-α)in the observation group were lower than those in the control group(P<0.05).There was no statis‐tically significant difference in intestinal barrier function indicators between the two groups before treatment(P>0.05).After 1 week of treatment,the serum levels of D-lactic acid(D-LA),endotoxin(ET)and diamine oxidase(DAO)in the observation group were lower than those in the control group(P<0.05).Conclu-sion Houpo Qiwu Decoction combined with neostigmine acupoint injection exerts significant clinical efficacy in the treatment of EPII.It can obviously alleviate clinical symptoms,reduce inflammatory response and regulate intestinal barrier function in patients.
何立春;张玉蓉;李兴禹
甘肃省酒泉市金塔县人民医院普外科(甘肃 酒泉 735300)甘肃省酒泉市金塔县人民医院普外科(甘肃 酒泉 735300)甘肃省酒泉市金塔县人民医院普外科(甘肃 酒泉 735300)
腹部手术早期炎性肠梗阻厚朴七物汤新斯的明穴位注射
Abdominal surgeryEarly inflammatory ileusHoupo Qiwu DecoctionNeostigmine acupoint injection
《中国肛肠病杂志》 2026 (1)
10-13,4
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