2012～2022年杭州市上城区恶性肿瘤发病趋势分析OA

Objective:To analyze the prevalence and trends of malignant tumors in Shangcheng District,Hangzhou,from 2012 to 2022.Methods:Using tumor registry data and demographic information for Shangcheng District,Hangzhou from 2012 to 2022,the incidence and ranking of malignant tumors were calculated.The incidence rate and age-standardized inci-dence rate by Chinese standard population in 2000(ASRC)were calculated.Joinpoint regression analysis was performed to calculate the average annual percent change(AAPC)to ex-plore trends in the incidence of malignant tumors in Shangcheng District.Results:During 2012～2022 in Shangcheng District,the crude incidence(per 100,000)of malignant tumors was 486.92 overall,499.16 for males,and 474.94 for females.The ASRC were 272.62,257.02,and 293.72 per 100,000,respectively.The incidence of malignant tumors increased significantly after the age of 40.In Shangcheng District,the most common cancers were lung caner,thyroid cancer,breast cancer in women,colorectal cancer and stomach cancer.A significant rising trend in malignant tumor inci-dence was observed among women(ASRC:AAPC=2.31%,P=0.009).Analysis of the top five malignant tumors showed a significant upward trend in lung cancer(AAPC=11.97%)and stomach cancer(AAPC=4.28%).Gender-spe-cific analysis revealed that lung cancer(ASRC:AAPC=11.82%,P<0.001)and prostate cancer(ASRC:AAPC=11.84%,P<0.001)in males increased,while lung cancer(ASRC:AAPC=20.95%,P<0.001)and colorectal cancer(ASRC:AAPC=14.34%,P=0.016)in females demonstrated consistent annual growth.Conclusion:The disease bur-den of cancer in Shangcheng District was still heavy,with lung cancer,thyroid cancer,breast cancer(in women),colorec-tal cancer,and stomach cancer constituting the main threats to residents′ health.Cancer prevention efforts should focus on a-dults over 40,with intensified early screening for prostate cancer in men and breast cancer in women.