西南区域高海拔地区世居高原自然人群队列研究进展OA

In recent years,the burden of chronic diseases in China has been continuously escalating with significant regional disparities.The local indigenous populations residing in the high-altitude areas of Southwest China have developed unique physiological and genetic traits due to specific geographical and multi-ethnic factors,confronting health challenges such as cardiovascular diseases and metabolic disorders.To conduct a comprehensive analysis the disease distribution patterns and potential exposure factors among this population and to address the data gaps regarding the prevalence of non-communicable diseases(NCDs),risk factors,and related conditions in resource-limited areas with multi-ethnic groups.This study relies on the china multi-ethnic cohort(CMEC)study has established high-altitude natural population cohorts in Lijiang(Yunnan),Aba(Sichuan),and Lhasa(Tibet)to systematically collect baseline data.While health outcomes were monitored through standardized follow-ups to reveal the prevalence rates and their primary risk factors of chronic diseases in high-altitude regions.To explore the impacts of dietary patterns and lifestyle on the metabolic health of plateau populations,discover novel intervention technologies and strategies for chronic diseases,and provide theoretical support for the prevention and control of chronic diseases in Southwest China and even the whole country.