首页|期刊导航|肝胆胰外科杂志|肝动脉栓塞序贯微波消融治疗肝血管瘤效果观察

肝动脉栓塞序贯微波消融治疗肝血管瘤效果观察OA

Efficacy of transcatheter arterial embolization sequential microwave ablation in the treatment of hepatic hemangioma

中文摘要英文摘要

目的 探讨肝动脉栓塞(TAE)序贯微波消融(MWA)治疗肝血管瘤(HH)的临床疗效及安全性.方法 回顾性分析2018年1月至2024年12月首都医科大学附属北京佑安医院肝病与肿瘤介入治疗中心收治的60例HH患者(肿瘤最大径5~10 cm)的临床资料,共65个病灶.所有患者均接受TAE序贯MWA治疗,记录序贯治疗后24 h内并发症发生情况,并在序贯治疗后6个月通过增强CT或增强MRI评估病灶大小(最大径与体积)变化,计算技术有效率(以肿瘤体积缩小≥50%为标准).结果 TAE序贯MWA治疗的技术成功率为100%.序贯治疗后6个月,HH最大径由治疗前的7.0(5.7,8.0)cm缩小至4.5(3.5,5.4)cm(P<0.001);HH体积由111.5(61.9,182.5)cm3 缩小至34.6(14.8,61.9)cm3(P<0.001).TAE序贯MWA治疗的技术有效率为86.2%(56/65),所有治疗前存在腹部不适症状的患者(7例)症状均获得缓解.安全性方面,31例(51.7%)患者在序贯治疗后24 h内出现轻微并发症,包括腹痛(16例)、一过性血红蛋白尿(12例)、低热(1例)及肝包膜下少量出血(2例),所有并发症经对症处理后均好转,未发生严重并发症或死亡病例.结论 TAE序贯MWA治疗HH可有效缩小病灶并缓解症状,且安全性良好,是一种微创、可靠的治疗方法.

Objective To investigate the clinical efficacy and safety of transcatheter arterial embolization(TAE)sequential microwave ablation(MWA)for hepatic hemangioma(HH).Methods A retrospective analysis was conducted on the clinical data of 60 patients with HH(diameter ranging from 5.0 to 9.9 cm)treated in Interventional Therapy Center for Oncology,Beijing You'an Hospital,Capital Medical University,from January 2018 to December 2024,involving a total of 65 lesions.All patients received TAE sequential MWA.The occurrence of complications within 24 hours after sequential treatment was recorded.The changes in lesion size(maximum diameter and volume)were evaluated by enhanced CT or MRI 6 months after sequential treatment,and the technical effective rate was calculated(with a volume reduction of≥50%as the standard).Results The technical success rate of TAE sequential MWA was 100%.Six months after sequential treatment,the maximum diameter of HH decreased from 7.0(5.7,8.0)cm to 4.5(3.5,5.4)cm(P<0.001);The volume decreased from 111.5(61.9,182.5)cm3 to 34.6(14.8,61.9)cm3(P<0.001).The technical efficacy rate of TAE sequential MWA was 86.2%(56/65).All patients(7 cases)with preoperative abdominal discomfort experienced symptom relief.Regarding complications,31 patients(51.7%)experienced minor complications within 24 hours after sequential treatment,including abdominal pain(16 cases),transient hemoglobinuria(12 cases),low-grade fever(1 case),and minor subcapsular hepatic hemorrhage(2 cases).All complications resolved with symptomatic management,with no severe complications or fatalities occurred.Conclusion TAE sequential MWA for HH may effectively reduce lesion size and alleviate symptoms with good safety,which representing a minimally invasive and reliable treatment strategy.

安奕轩;李建军;张永宏;袁春旺;鹿宁宁;马良;高文峰;何宁;杨晓珍;生守鹏;扈彩霞;孙斌

首都医科大学附属北京佑安医院肝病与肿瘤介入治疗中心,北京 100069首都医科大学附属北京佑安医院肝病与肿瘤介入治疗中心,北京 100069首都医科大学附属北京佑安医院肝病与肿瘤介入治疗中心,北京 100069首都医科大学附属北京佑安医院肝病与肿瘤介入治疗中心,北京 100069首都医科大学附属北京佑安医院肝病与肿瘤介入治疗中心,北京 100069首都医科大学附属北京佑安医院肝病与肿瘤介入治疗中心,北京 100069首都医科大学附属北京佑安医院肝病与肿瘤介入治疗中心,北京 100069首都医科大学附属北京佑安医院肝病与肿瘤介入治疗中心,北京 100069首都医科大学附属北京佑安医院肝病与肿瘤介入治疗中心,北京 100069首都医科大学附属北京佑安医院肝病与肿瘤介入治疗中心,北京 100069首都医科大学附属北京佑安医院肝病与肿瘤介入治疗中心,北京 100069首都医科大学附属北京佑安医院肝病与肿瘤介入治疗中心,北京 100069

医药卫生

肝血管瘤肝动脉栓塞微波消融微创治疗

hepatic hemangiomatranscatheter arterial embolizationmicrowave ablationminimally invasive treatment

《肝胆胰外科杂志》 2026 (2)

110-114,5

首都卫生发展科研专项(2024-1-5041)科技创新2030——"新一代人工智能"重大项目(2021ZD0113200).

10.11952/j.issn.1007-1954.2026.02.006

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