一例感染坏死性胰腺炎并发结肠出血的MDT诊治OA
Diagnosis and treatment for one patient with infected necrotizing pancreatitis complicated by colonic hemorrhage under multidisciplinary team
胰腺假性囊肿(PPC)和包裹性坏死(WON)作为急性胰腺炎(AP)后期(≥4周)的局部并发症,可继发感染、出血,导致感染性胰腺坏死(IPN)、囊内出血、消化道出血等并发症.其病因复杂,并发症多样,诊断困难,病死率高.本文报道一例慢性胰腺炎急性发作,先后并发PPC出血、IPN及结肠出血的复杂病例.该患者虽经多学科团队(MDT)指导下的保守治疗与内镜干预,仍反复出血、感染难以控制,最终在血流动力学不稳定的情况下行急诊手术(胰体尾切除+脾切除+结肠脾区切除+部分胃切除+结肠吻合+回肠造瘘),术后恢复良好.结合文献,本文重点探讨此类胰腺炎复杂并发症的MDT协作机制、个体化治疗策略的选择及手术干预时机的把握,以期为临床提供参考.
Pancreatic pseudocysts(PPC)and walled-off necrosis(WON)are local complications in the later stages(≥4 weeks)of acute pancreatitis(AP),which can be complicated by secondary infection and hemorrhage,leading to further complications such as infected pancreatic necrosis(IPN),intracystic hemorrhage and gastrointestinal bleeding.Due to the complex etiology,varied presentations,diagnostic challenges and high mortality,these conditions require rigorous clinical attention.This article presented a case of chronic pancreatitis with acute exacerbation,complicated successively by hemorrhage within pancreatic cysts,IPN and colonic hemorrhage.Despite multidisciplinary team(MDT)-guided conservative management and endoscopic intervention,the patient experienced recurrent bleeding and uncontrolled infection,ultimately necessitating emergency surgery(distal pancreatectomy+splenectomy+splenic flexure resection+partial gastrectomy+colonic anastomosis+ileostomy)under hemodynamically unstable conditions.The patient recovered well postoperatively.In conjunction with a literature review,this article focuses on the MDT collaborative approach,the selection of individualized treatment strategies,and the timing of surgical intervention for complex complications of pancreatitis,aiming to provide clinical reference.
王传云;吴双燕;七林拉姆;丁伟;杨耀雄;王泽晗;谢富佳;鲍国清;杨斌
昆明医科大学第一附属医院 肝胆外科,云南 昆明 650032昆明医科大学第一附属医院 肝胆外科,云南 昆明 650032昆明医科大学第一附属医院 肝胆外科,云南 昆明 650032昆明医科大学第一附属医院 肝胆外科,云南 昆明 650032昆明医科大学第一附属医院 肝胆外科,云南 昆明 650032昆明医科大学第一附属医院 肝胆外科,云南 昆明 650032昆明医科大学第一附属医院 胃肠与疝外科,云南 昆明 650032昆明医科大学第一附属医院 肝胆外科,云南 昆明 650032昆明医科大学第一附属医院 肝胆外科,云南 昆明 650032
医药卫生
胰腺炎感染性坏死多学科团队个体化治疗结肠出血
pancreatitisinfected necrosismultidisciplinary teamindividualized treatmentcolonic hemorrhage
《肝胆胰外科杂志》 2026 (2)
84-91,8
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