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内镜逆行胰胆管造影治疗胰管结石的要点评价OA

Evaluation of key points in endoscopic retrograde cholangiopancreatography for pancreatic duct stones

中文摘要英文摘要

胰管结石是慢性胰腺炎的特征性病理改变,结石可导致胰液排泄受阻,引发胰管及胰腺实质高压,损害胰腺腺体结构及内外分泌功能,加速慢性胰腺炎进程,形成慢性胰腺炎-结石-胰腺高压的恶性循环.外科手术曾是我国治疗胰管结石的主要方法,但存在创伤大、早期并发症发生率高等缺点.而内镜逆行胰胆管造影(ERCP)置入胰管支架可以降低胰管压力,达到缓解临床症状的基本要求,也能取净结石、解除狭窄、通畅引流,同时具有创伤小、安全性高、重复性强等优点,逐渐成为治疗胰管结石的首选方法.ERCP操作中虽然存在出血、穿孔、取石失败、支架移位等多种并发症,但熟练掌握扩张球囊、碎石网篮、取石网篮和胰管支架等器械的操作技巧及适应证,可提高取石成功率,降低并发症发生率.本文将总结我们20余年治疗胰管结石的经验,结合国内外相关文献,对ERCP治疗胰管结石的适应证、并发症及操作技巧进行论述,提出直径≤5 mm结石选择单纯ERCP取石,直径>5 mm结石可联用碎石等技术,合并胰管狭窄可先置入全覆膜金属支架,为胰管结石的规范化ERCP治疗提供参考.

Pancreatic duct stone is a characteristic pathological manifestation of chronic pancreatitis.Stone can cause obstruction of pancreatic juice excretion,leading to high pressure of pancreatic duct and pancreatic parenchyma,damaging the structure and endocrine function of pancreatic glands,accelerating the progression of chronic pancreatitis,and forming the vicious cycle of chronic pancreatitis stones with pancreatic high pressure.Surgical treatment is the main method for treating pancreatic duct stone in China,but it has many disadvantages such as high trauma and high incidence of early complications.Endoscopic retrograde cholangiopancreatography(ERCP)can reduce pancreatic duct pressure and meet the basic requirements of relieving clinical symptoms.ERCP can also remove stones,relieve stenosis,and facilitate pancreatic juice drainage.It gradually becomes the preferred method for the treatment of pancreatic duct stone for the advantages of minimal trauma,high safety,and strong repeatability.ERCP also has various complications such as bleeding,perforation,failed stone retrieval,and stent displacement.It is important to master the operating techniques and indications of instruments such as dilation balloons,stone baskets,stone retrieval baskets,and pancreatic duct stents.In this article we will summarize our experience of more than 20 years in treating pancreatic duct stones,and discuss the indications,complications,and operational techniques of ERCP treatment for pancreatic duct stones based on domestic and foreign relevant literature.It proposes that ERCP can be chosen directly to remove pancreatic duct stone with a diameter less than or equal 5 mm,fragmentation techniques can be used for stone with a diameter greater than 5mm,and fully covered metal stent can be used to treat pancreatic duct structure,providing reference for standardized ERCP treatment of pancreatic duct stone.

张诚;张桂信;杨玉龙

大连医科大学附属第二医院肝胆胰外科,辽宁 大连 116021同济大学附属东方医院胆石病中心,上海 200120大连医科大学附属第二医院肝胆胰外科,辽宁 大连 116021

医药卫生

胰管结石慢性胰腺炎胰管狭窄内镜逆行胰胆管造影经口胰管镜检查体外冲击波碎石

pancreatic duct stonechronic pancreatitispancreatic duct strictureendoscopic retrograde cholangiopancreatographyperoral pancreaticoscopyextracorporeal shock wave lithotripsy

《肝胆胰外科杂志》 2026 (1)

1-6,6

10.11952/j.issn.1007-1954.2026.01.001

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