凉血十味片联合羟苯磺酸钙胶囊治疗非增殖性糖尿病视网膜病变的临床研究OA
Clinical Study on the Treatment of Nonproliferative Diabetic Retinopathy with Liangxue Shiwei Tablets Combined with Calcium Dobesilate Capsules
目的:探究与分析凉血十味片联合羟苯磺酸钙胶囊治疗非增殖性糖尿病视网膜病变的临床效果.方法:选择扎兰屯市人民医院 2021 年 5 月—2023 年 9 月收治的 98 例非增殖性糖尿病视网膜病变患者,采取随机数字表法分为对照组和观察组,每组 49 例,所有患者均给予降糖,控制血脂、血压治疗,行饮食指导、运动干预等以保证血糖水平平稳,对照组给予羟苯磺酸钙胶囊治疗,观察组在对照组的基础上联合凉血十味片治疗.两组均治疗 3 个月.对比两组临床疗效、治疗前后视力、视网膜病变指标及中医证候积分,同时对比两组不良反应发生情况.结果:观察组临床总有效率比对照组高(P<0.05).治疗后,观察组视力较对照组高,渗出灶面积、出血灶面积较对照组小,微血管瘤数量较对照组少,视物模糊、视物变形、眼干耳鸣、头晕头痛等评分较对照组低(P<0.05).两组不良反应发生率比较,差异无统计学意义(P>0.05).结论:凉血十味片联合羟苯磺酸钙胶囊治疗非增殖性糖尿病视网膜病变患者具有突出的临床效果,视网膜病变指标得到了明显的改善,中医症状明显减轻,且不明显增加不良反应.
Objective:To explore and analyze the clinical effect of Liangxue Shiwei Tablets combined with Calcium Dobesilate Capsules in the treatment of nonproliferative diabetic retinopathy.Method:A total of 98 patients with nonproliferative diabetic retinopathy admitted to Zhalantun People's Hospital from May 2021 to September 2023 were selected and divided into control group and observation group by random number table method,with 49 cases in each group.All patients were given hypoglycemic,lipid and blood pressure control treatments,dietary guidance,exercise intervention,etc.to ensure stable blood glucose levels.The control group was treated with Calcium Dobesilate Capsules.The observation group was treated with Liangxue Shiwei Tablets in combination with the control group.Both groups were treated for 3 months.The clinical efficacy,visual acuity,retinal lesion indicators and traditional Chinese medicine syndrome scores of the two groups before and after treatment were compared.At the same time,the occurrence of adverse reactions in the two groups was also compared.Result:The total clinical effective rate of the observation group was higher than that of the control group(P<0.05).After treatment,the visual acuity of the observation group was higher than that of the control group,the area of exudate foci and bleeding foci were smaller than those of the control group,the number of microhemangiomas was less than that of the control group,and the scores of blurred vision,distorted vision,dry eyes,tinnitus,dizziness and headache were lower than those of the control group(P<0.05).There were no statistically significant differences in the incidence of adverse reactions between the two groups(P>0.05).Conclusion:The combination of Liangxue Shiwei Tablets combined with Calcium Dobesilate Capsules has a remarkable clinical effect in the treatment of patients with nonproliferative diabetic retinopathy.The retinopathy indicators have been significantly improved,the symptoms of traditional Chinese medicine have been significantly alleviated,and no significant increase in adverse reactions.
塔拉
扎兰屯市人民医院神经内二科 内蒙古 扎兰屯 162650
凉血十味片羟苯磺酸钙胶囊非增殖性糖尿病视网膜病变不良反应
Liangxue Shiwei TabletsCalcium Dobesilate Capsules Nonproliferative diabetic retinopathyAdverse reaction
《中国医学创新》 2026 (1)
73-76,4
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