C反应蛋白/白蛋白比值与D-二聚体联合检测对妊娠合并急性胰腺炎病情严重程度的预测价值OA
Predictive value of the combined detection of C-reactive protein-to-albumin ratio and D-dimer on the severity of acute pancreatitis in pregnancy
目的 探讨血清C反应蛋白/白蛋白比值(CAR)、D-二聚体及二者联合检测预测妊娠合并急性胰腺炎(APIP)病情严重程度的价值.方法 收集2021年1月至2023年12月间我院APIP患者及同期分娩的正常妊娠者(健康对照组)的临床资料.根据APIP病情严重程度将患者分为非重症组、重症组;根据病因分为胆源型组、高脂血症型组、特发型组.用logistic回归分析影响APIP病情严重程度的危险因素及其诊断效能.结果 CAR、D-二聚体是影响APIP病情严重程度的独立危险因素.CAR和D-二聚体联合检测受试者操作特征曲线下面积最大,且灵敏度、特异度等诊断效能均优于单独检测.结论 CAR及D-二聚体是APIP病情严重程度的独立危险因素,且二者联合检测可作为APIP病情严重程度的良好预测指标.
Objective To explore the predictive significance of serum C-reactive protein-to-albumin ratio(CAR),D-dimer,and their combined detection for the severity of disease in pregnant women with acute pancreatitis(APIP).Methods Data of patients with APIP and normal pregnant women in our hospital from January 2021 to December 2023 were collected.Patients were grouped according to the severity of APIP into non-severe,severe,and healthy control groups,or according to the etiology into biliary type,hyperlipidemia type,and idiopathic type groups.Logistic regression analysis was used to analyze the risk factors and diagnostic efficacy of APIP severity.Results CAR and D-dimer were independent risk factors for disease severity.The combined detection of CAR and D-dimer had the largest area under the curve and better diagnostic efficacy(sensitivity,specificity,etc.)than other single predictions.Conclusion CAR and D-dimer are independent risk factors for disease severity,and their combined detection can be used as a good predictor of APIP severity.
刘英男;严丽梅
中国医科大学附属盛京医院妇产科,沈阳 110004中国医科大学附属盛京医院妇产科,沈阳 110004
医药卫生
妊娠合并急性胰腺炎C反应蛋白/白蛋白比值D-二聚体联合预测
acute pancreatitis in pregnancyC-reactive protein-to-albumin ratioD-dimercombined prediction
《中国医科大学学报》 2026 (1)
75-79,5
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