细胞分布宽度与白蛋白比值对免疫受损宿主肺炎预后的预测价值OA

Objective To investigate the predictive value of the ratio of plasma red blood cell distribution width(RDW)to serum al-bumin(Alb)(RAR)for the prognosis in patients with immunocompromised host pneumonia(ICHP).Methods ICHP patients who visited the Respiratory and Critical Care Department in Jilin Province People's Hospital were enrolled and categorized into survival and non-survival groups based on their 28-day outcomes.General information and experimental examination indicators of patients were used to evaluate the re-lationship between RAR and 28-day mortality rate through univariate analysis,multivariate logistic regression analysis,subject operating curve,and survival analysis.Results Compared with the survival group,the age,disease duration,proportion of chronic kidney disease,pro-portion of chronic lung disease,ground glass opacities,SOFA score,APACHE Ⅱscore,presence of respiratory distress syndrome,RDW,and RAR were higher in the death group.In contrast,the oxygenation index,Alb,Red blood cell count were lower.Multivariate regression analysis showed that RAR was independently associated with 28-day mortality in ICHP patients.The mortality risk of RAR was AUC 0.770(95%CI 0.725～0.815),with a sensitivity of 0.806 and a specificity of 0.587 at an optimal cutoff value of 4.232.Conclusion RAR has good pre-dictive value for the 28-day prognosis of ICHP patients.