阿尔茨海默病抗Aβ单克隆抗体治疗的护理OA
Nursing management of anti-Aβ monoclonal antibody therapy of Alzheimer's disease
抗β-淀粉样蛋白(Aβ)单克隆抗体是目前阿尔茨海默病(AD)疾病修饰治疗的重要策略,但是可能引起输液反应、淀粉样蛋白相关影像学异常(ARIA)等不良反应,治疗前严格评估、注射期间严密监测及护理、输注后长期随访指导对于保证患者安全具有重要意义.本文系统综述了抗Aβ单克隆抗体治疗的不良反应与护理管理策略,为安全使用抗Aβ单克隆抗体提供帮助.
Anti-β-amyloid(Aβ)monoclonal antibodies offer a promising therapeutic approach to treating Alzheimer's disease(AD),but they carry risks such as infusion reactions and amyloid-related imaging abnormalities(ARIAs),necessitating vigilant nursing oversight.Therefore,pre-treatment rigorous evaluation,close monitoring and nursing during infusion,and post-infusion follow-up and guidance are of great significance to ensuring patients' safety.This review summarizes current advances,adverse effects,and nursing strategies in AD immunotherapy to enhance clinical safety.
刘雪婷;李青莉;屈彦
西安交通大学第一附属医院神经内科,陕西西安 710061西安交通大学第一附属医院神经内科,陕西西安 710061西安交通大学第一附属医院神经内科,陕西西安 710061
医药卫生
阿尔茨海默病(AD)β-淀粉样蛋白(Aβ)免疫治疗单克隆抗体护理
Alzheimer's disease(AD)β-amyloid(Aβ)immunotherapymonoclonal antibodynursing
《西安交通大学学报（医学版）》 2026 (1)
32-38,7
西安交通大学第一附属医院横向课题(No.HXIIT2024089)Supported by the Lateral Research Project of The First Affiliated Hospital of Xi'an Jiaotong University(No.HXIIT2024089)
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