化妆品局部毒性动物试验的影响因素分析OA
Analysis of factors influencing local toxicity animal testing of cosmetics
化妆品的安全性评价已成为关注的焦点,而局部动物毒理学试验是化妆品安全性评估中的重要环节.重点分析了动物饲养因素、人为操作因素以及样品因素对皮肤刺激性试验、急性眼刺激性试验、皮肤变态反应试验及皮肤光毒性试验结果的影响,旨在提高测试结果的准确性.
With increasing public attention on cosmetic safety evaluation,local toxicity animal testing remains a crucial component in assessing product safety.The effects of animal husbandry conditions,human operational factors,and sample characteristics on the outcomes of skin irritation,acute eye irritation,skin sensitization,and skin phototoxicity tests were analyzed.The objective is to improve the reliability and accuracy of toxicity testing results and provide scientific support for enhancing cosmetic safety assessment practices.
孙淑蓉;邱俊坚;张晓萌
珀莱雅化妆品股份有限公司,浙江 杭州 310018浙江省药品化妆品审评中心,浙江 杭州 310018苏州华搏生物检测有限公司,江苏 苏州 215000
化学化工
化妆品动物毒理学影响因素分析
cosmeticsanimal toxicologyinfluencing factorsanalysis
《日用化学品科学》 2026 (1)
76-79,89,5
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