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基于伏毒理论探讨慢性胃炎炎癌转化病机与防治OA

Exploration of the pathogenesis,prevention and treatment of"inflammation-cancer transformation"in chronic gastritis based on the concept of"latent toxicity"

中文摘要英文摘要

探讨"伏毒"理论视域下慢性胃炎"炎癌转化"之病机演变."伏毒"理论认为邪伏胃络、胃失和降,痰瘀交织,郁积成毒,伏毒内阻、成积致岩是慢性胃炎"炎癌转化"的病机演变过程.临床应灵活辨识病机,尽早干预以截断病程发展变化.提出祛邪通络、调畅气机,化痰活血、行气解郁,清热解毒、消肿散结为慢性胃炎"炎癌转化"的防治方法,以期为慢性胃炎与胃癌"炎癌转化"提供预防及诊治思路.

The theory of"latent toxicity"is of significant importance in explaining the pathogenesis of chronic gastritis progressing to gastric cancer.Under the framework of this theory,this study is aimed at exploring the pathogenesis and treatment methods for"inflammation-cancer transformation"in chronic gastritis,based on the prolonged presence of pathogenic factors that transform into toxins.It posits that the pathogenic factors lurk in the gastric channels,leading to disharmony and failure of gastric function;the intermingling of phlegm and blood stasis,and accumulating into toxins;the internal obstruction caused by hidden toxins,and resulting in hard masses,and the three phases represent the evolutionary process of"inflammation-cancer transformation"in chronic gastritis.The theory advocates for a flexible clinical differentiation of its pathogenesis,with an early intervention to disrupt the progression of the disease.It suggests strategies for the prevention and treatment of"inflammation-cancer transformation"in chronic gastritis,such as expelling pathogenic factors and unblocking channels,regulating qi flow,resolving phlegm and promoting blood,activating qi circulation to relieve depression,and clearing heat and detoxifying to reduce swelling and dissipate masses.This study is expected to provide preventive and diagnostic insights for the transformation between chronic gastritis and gastric cancer.

曹子琪;李廷荃

山西中医药大学第一临床学院,山西 晋中 030619山西中医药大学附属医院,太原 030024

医药卫生

伏毒理论慢性胃炎炎癌转化病机防治策略

theory of latent toxicitychronic gastritisinflammation-cancer transformationpathogenesisprevention and treatment strategies

《吉林中医药》 2026 (1)

34-38,5

国家自然科学基金面上项目(81874474)国家中医药管理局中医药领军人才培养项目、岐黄学者支持项目(国中医药人教函[2022]号)萧氏脾胃学术流派传承工作室(2020PY-LP-08)

10.13463/j.cnki.jlzyy.2026.01.007

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