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基于"内毒"探析慢性冠脉综合征中医病机与辨治OA

Analysis on the pathogenesis,syndrome differentiation,and treatment of chronic coronary syndrome in Chinese medicine based on the theory of"endogenous toxicity"

中文摘要英文摘要

慢性冠脉综合征(CCS)虚实夹杂,多因虚而生邪、因瘀而酿毒、因毒而致病,内毒蕴结,耗伤心体血脉是主要病机,发病率高、病死率高.虚损以宗气为著,邪实在痰瘀、内毒互化,虚-瘀-毒导致病程发展难辨.治疗以调补宗气、祛瘀防毒、清解内毒为主,施调补宗气法、祛瘀防毒法、内毒清解六法等治之,以期为慢性冠脉综合征辨证用药提供参考.

Chronic coronary syndrome,as a disease with high morbidity and mortality rate,has imposed a tremendous burden on patients'quality of life and national economy.In terms of its pathogenesis,the disease is characterized by an intermingled deficiency and excess,mostly due to the fact that deficiency leads to pathogenic factors,blood stasis brews into toxicity,and toxicity induces the disease.In consequence,endogenous toxicity accumulates in the body,consuming and impairing the heart and blood vessels,which counts as its primary pathogenesis and promotes the onset and deterioration of the disease.Deficiency is most prominent in pectoral qi,and the excessive pathogenic factors are manifested as the mutual transformation of phlegm,blood stasis,and endogenous toxins,therefore the transformation of deficiency,blood stasis and toxins into each other leads to the extremely complicated progression of the disease.It is proposed that its treatment be focused on regulating and tonifying pectoral qi,eliminating blood stasis and preventing toxins,and clearing and resolving endogenous toxicity.This study is aimed at providing a reference for the syndrome differentiation and medication in the treatment of chronic coronary syndrome.

何海龙;韩雨桐;郭彬;王雅婧;谢连娣

北京中医药大学研究生院,北京 100029||中日友好医院心脏科心衰中心,北京 100029北京中医药大学东方医院,北京 100079北京中医药大学东方医院,北京 100079北京中医药大学研究生院,北京 100029北京中医药大学东方医院,北京 100079

医药卫生

慢性冠脉综合征虚气留滞内毒血瘀病机

chronic coronary syndromedeficient-qi retentionendogenous toxicityblood stasispathogenesis

《吉林中医药》 2026 (1)

25-29,5

第五批全国中医临床优秀人才研修项目(国中医药人教函[2022]1号)

10.13463/j.cnki.jlzyy.2026.01.005

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