基于"正虚毒泛"探讨胃解痉多肽表达化生中医内涵及中药调控OA
Exploration of the Chinese medicine connotations and regulation of gastric antispasmodic polypeptide-expressing metaplasia based on the theory of"diffusion of toxins due to deficient vital qi"
胃解痉多肽表达化生(SPEM)作为一种新型胃黏膜化生形式,是胃癌前病变的初始阶段和关键病理环节,明确其发病机制并提出切实可行的调控策略意义重大.基于"正虚毒泛"理论探讨胃解痉多肽表达化生在发生发展、甚至癌变过程中的中医内涵,提出相对应的中药调控策略并分析其科学性,以期为胃解痉多肽表达化生的干预和治疗提供新的思路.
Gastric antispasmodic polypeptide-expressing metaplasia(SPEM),as a novel form of gastric mucosal metaplasia,is the initial step and key pathological link of precancerous lesions of gastric cancer.It is of great significance to clarify its pathogenesis and propose practical regulatory strategies for it.Based on the theory of"deficiency of vital energy and excessive toxicity",this study explores the connotations of traditional Chinese medicine in the occurrence,development and even carcinogenesis of gastric SPEM,proposes corresponding traditional Chinese medicine regulatory strategies for it and analyzes their scientific natures,with the aim of providing new ideas for the intervention and treatment of gastric SPEM.
吴思雨;胡雨萌;隋博文
黑龙江中医药大学研究生院,哈尔滨 150040黑龙江中医药大学研究生院,哈尔滨 150040黑龙江中医药大学附属第一医院肿瘤一科,哈尔滨 150040
医药卫生
正虚毒泛胃解痉多肽表达化生中医内涵中药调控
diffusion of toxins due to deficient vital qigastric spasmolytic polypeptide-expressing metaplasiaconnotation of TCMregulation of Chinese medicine
《吉林中医药》 2026 (1)
20-24,5
国家中医药管理局第五批全国中医临床优秀人才项目(国中医药人教函[2022]1号)
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